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MetabolomicsMetabolomics identifies multiple candidate biomarkers to diagnose and stage human African trypanosomiasis
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood and lymphatics whilst for stage 2, parasites are found beyond the blood-brain barrier in the cerebrospinal flui...
2018-01-24 | MTBLS413 | MetaboLights
GenomicsChromosomal rearrangement in African Trypanosomes
Structural chromosomal rearrangements mirror the evolutionary differences between African trypanosomes.
PRJEB30325 | ENA
ProteomicsMapping diversity in African trypanosomes using high resolution spatial proteomics
African trypanosomes are dixenous eukaryotic parasites that impose a significant human and veterinary disease burden on sub-Saharan Africa. Diversity between species and life-cycle stages is concomitant with distinct host and tissue tropisms within this group. Here, the spatial proteomes of two Afri...
ORGANISM(S): Trypanosoma brucei Trypanosoma congolense 
2023-10-22 | PXD035426 | Pride
Trypanosoma brucei Hyperlopit African trypanosomes Spatial proteome Parasite diversification Speciation Trypanosoma congolense Protein localisation 
ProteomicsA novel factor integrating transcription and repression of surface antigen genes in African trypanosomes
Mass spectrometry data and proteomic results relating to the manuscript: A novel factor integrating transcription and repression of surface antigen genes in African trypanosomes
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2025-06-26 | MSV000098335 | MassIVE
ProteomicspH taxis in African trypanosomes
The collective movement of African trypanosomes on semi-solid surfaces, known as social motility, is presumed to be due to migration factors and repellents released by the parasites. Here we show that procyclic (insect midgut) forms acidify their environment as a consequence of glucose metabolism, g...
ORGANISM(S): Trypanosoma brucei 
2022-02-17 | PXD030766 | Pride
Chemotaxis Cyclic amp Ph Adenylate cyclase Trypanosoma brucei Social motility Tsetse 
TranscriptomicsIn vitro generation of human high-density-lipoprotein-resistant Trypanosoma brucei brucei
The host range of African trypanosomes is influenced by innate protective molecules in the blood of primates. A subfraction of human high-density lipoprotein (HDL) containing apolipoprotein A-I, apolipoprotein L-I, and haptoglobin-related protein is toxic to Trypanosoma brucei brucei but not the hum...
ORGANISM(S): Trypanosoma brucei brucei 
2007-07-04 | E-GEOD-8369 | biostudies-arrayexpress
GenomicsParse scRNA-seq of African trypanosomes
Parse scRNA-seq of African Trypanosomes
PRJEB72378 | ENA
UnknownCytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage.
Not available
S-EPMC3983053 | biostudies-literature
UnknownAfrican trypanosomes.
Not available
S-EPMC6489224 | biostudies-literature
UnknownTaxonomic re-evaluation of African anuran trypanosomes with the redescription and molecular diagnosis of Trypanosoma (Trypanosoma) nelspruitense Laveran, 1904 and Trypanosoma (Haematomonas) grandicolor Pienaar, 1962.
Not available
S-EPMC10260303 | biostudies-literature
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