Trypanosoma brucei spp. develop into mammalian-infectious metacyclic trypomastigotes inside tsetse salivary glands. Besides acquiring a variant surface glycoprotein (VSG) coat, little is known about the metacyclic expression of invariant surface antigens. Proteomics analyses of saliva from T. brucei...
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
Trypanosoma brucei causes African trypanosomosis to humans and cattle, against which there are no effective vaccines or drugs. The tsetse fly Glossina morsitans morsitans is the primary vector of the species of T. brucei group. At the moment there is limited knowledge on how trypanosomes adapt to a...
