Sort   by:  
 Page size 
ProteomicsNascent alt-protein chemoproteomics reveals a repressor of ribosome biogenesisNascent alt-protein chemoproteomics reveals a repressor of pre-60S assembly
Many unannotated microproteins and alternative proteins (alt-proteins) have recently been found to be co-encoded with canonical proteins, but few of their functions are known. Motivated by the hypothesis that alt-proteins undergoing regulated synthesis could play important cellular roles, we develop...
ORGANISM(S): Homo sapiens (Human) 
2022-09-13 | PXD026880 | Pride
Human hek 293t Lc-ms/ms 
UnknownNascent alt-protein chemoproteomics reveals a pre-60S assembly checkpoint inhibitor.
Not available
S-EPMC9423127 | biostudies-literature
UnknownProduction of the allergenic protein Alt a 1 by Alternaria isolates from working environments.
Not available
S-EPMC4344718 | biostudies-literature
UnknownZBTB40 is a telomere-associated protein and protects telomeres in human ALT cells.
Not available
S-EPMC10480536 | biostudies-literature
UnknownBrugia malayi: comparison of protective immune responses induced by Bm-alt-2 DNA, recombinant Bm-ALT-2 protein and prime-boost vaccine regimens in a jird model.
Not available
S-EPMC2763209 | biostudies-literature
ProteomicsComparative proteomic profiling of unannotated microproteins and alternative proteins in human cell lines
Ribosome profiling and mass spectrometry have revealed thousands of small and alternative open reading frames (sm/alt-ORFs) that are translated into polypeptides variously termed microproteins and alt-proteins in mammalian cells. Some micro-/alt-proteins exhibit stress-, cell type- and/or tissue-spe...
ORGANISM(S): Homo sapiens (Human) 
2020-06-05 | PXD018565 | Pride
Alt-protein Proteogenomics Microprotein Smorf 
UnknownAlternaria alternata allergen Alt a 1: a unique β-barrel protein dimer found exclusively in fungi.
Not available
S-EPMC3391610 | biostudies-literature
ProteomicsAlt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
While thousands of previously unannotated small and alternative open reading frames (alt-ORFs) have recently been revealed in the human genome, the functions of only a handful are currently known, leaving open the question of their biological significance as a class. Using a proteomic strategy for d...
ORGANISM(S): Homo sapiens (Human) 
2020-12-07 | PXD018268 | Pride
Human microprotein alt-protein phosphoproteomics 
ProteomicsAntagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Ongoing CAG expansions in Spinocerebellar ataxia type 1 (SCA1) and Huntington disease (HD) brains exacerbate disease.  Expansions involve aberrant repair of mutagenic slipped-DNAs, formed from single-stranded DNAs.  Whether singlestranded DNA-binding proteins prevent or facilitate expansions is unkn...
ORGANISM(S): Homo sapiens (Human) 
2023-10-13 | PXD044158 | Pride
Cag repeat expansion diseases  spinocerebellar ataxia type 1 (sca1)  huntington's disease (hd)  somatic cag repeat expansions  rpa (single-strand dna binding protein  alternative-rpa (alt-rpa)  dna repair Slipped-dnas  post-mortem brains Sca1 mice 
UnknownElucidation of immunological response and its regulatory network by P-TUFT-ALT-2: a promising fusion protein vaccine for human lymphatic filariasis.
Not available
S-EPMC5990782 | biostudies-literature
Sort   by:  
 Page size