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ProteomicsCross-linking/mass spectrometry analysis of the AOC complex
As a part of a study on how kinetochors are assembled at the centromeres of the chromosomes, cross-linking/mass spectrometry has been applied to investigate interactions between Okp1/ Ame1 heterodimer, which is part of the COMA complex, and CENP-A from Saccharomyces cerevisiae.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-10-30 | PXD009648 | Pride
Protein interaction Cenp-a Okp1 Centromere Cross-linking/mass spectrometry Ame1 
UnknownCdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle.
Not available
S-EPMC8341979 | biostudies-literature
UnknownRecognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex.
Not available
S-EPMC10702835 | biostudies-literature
UnknownThe kinetochore module Okp1<sup>CENP-Q</sup>/Ame1<sup>CENP-U</sup> is a reader for N-terminal modifications on the centromeric histone Cse4<sup>CENP-A</sup>.
Not available
S-EPMC6315295 | biostudies-literature
ProteomicsThe COMA complex plays a role in positioning Ipl1 activity proximal to Cse4 nucleosomes
Kinetochores are macromolecular protein complexes that ensure accurate chromosome segregation by linking chromosomes to spindle microtubules and integrating safeguard mechanisms. In yeast, the inner kinetochore, also known as Constitutive Centromere Associated Network (CCAN), is specifically establi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-04-12 | PXD011236 | Pride
Kinetochore  centromere  mtw  mif2  cross-linking  yeast 
ProteomicsAOCM-CPC - Kinetochores are macromolecular protein complexes that ensure accurate chromosome segregation by linking chromosomes to spindle microtubules and integrating safeguard mechanisms
Kinetochores are macromolecular protein complexes that ensure accurate chromosome segregation by linking chromosomes to spindle microtubules and integrating safeguard mechanisms. In yeast, the inner kinetochore, also known as Constitutive Centromere Associated Network (CCAN), is specifically establi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-04-12 | PXD011235 | Pride
Kinetochore  cpc  coma  cross-linking 
UnknownUnveiling the A-to-I mRNA editing machinery and its regulation and evolution in fungi.
Not available
S-EPMC11087585 | biostudies-literature
UnknownA cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.
Not available
S-EPMC4137059 | biostudies-literature
UnknownRecognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex
Not available
S-SCDT-10_15252-EMBR_202357702 | biostudies-other
UnknownStable centromere association of the yeast histone variant Cse4 requires its essential N-terminal domain.
Not available
S-EPMC11876619 | biostudies-literature
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