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Synovial Fibroblasts (SFs) are key pathogenic drivers in arthritis and their in vivo activation by TNF is sufficient to orchestrate full arthritic pathogenesis in animal models. TNF blockade has been efficacious for a large percentage of Rheumatoid Arthritis (RA) patients, although characterized by ...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-06 | PXD036283 | Pride
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis II
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis I
Amisulpride, a known antipsychotic drug, was identified to target synovial fibroblasts activation in arthritis through novel identified targets.
ORGANISM(S): Mus musculus 
2023-04-06 | GSE211137 | GEO
Amisulpride, a known antipsychotic drug, was identified to target synovial fibroblasts activation in arthritis through novel identified targets.
ORGANISM(S): Mus musculus 
2023-04-06 | GSE211132 | GEO
Blood methylomes of the first-episode schizophrenia patients differing in their response to amisulpride treatment (OPTiMiSE cohort)
ORGANISM(S): Homo sapiens 
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