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Polycyclic aromatic hydrocarbons (PAHs), some of the most widespread organic contaminants, are highly toxic to soil microorganisms. Whether long-term polluted soils can still respond to the fresh input of pollutants is unknown. In this study, the soil enzyme activity, soil microbial community struct...
2021-02-17 | MTBLS1196 | MetaboLights
For the GST pull-down of DRG ganglion, the GST- or Tmc7-GST-associated beads were further incubated with cell lysates derived from DRG ganglion. The pulled-down proteins were then separated by SDS-PAGE gel electrophoresis and subsequently stained with silver staining Kit. Finally, the target molecul...
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050466 |
Investigation of whole genome gene expression level changes in a Tim-3 knockdown RAW264.7 cell, compared to control siRNA transfected RAW264.7 cell. The Tim-3 knockdown of this cell render it hyper-reactive to TLR stimulation. Tim-3 knockdown analyzed in this study are further described in Li Y, Fen...
ORGANISM(S): Mus musculus 
In this study, we performed a comprehensive proteomic analysis of mango leaves inoculated with the leaf spot pathogen A. alternata. Down-regulated proteins during pathogen invasion and colonization were primarily associated with photosynthesis, the phenylpropanoid and flavonoid biosynthesis pathways...
ORGANISM(S): Mangifera indica (Mango) 
2025-05-07 | PXD060671 | Pride
Women are vulnerable to cervical diseases including normal control, HSIL and early stage cervical carcinoma . The parallel reaction monitoring mass spectrometry (PRM-MS) were used to qualitatively and quantitatively analyze the candidate differential proteins identified in our previous studies and t...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD022756 | Pride
Chromosome 5q deletions (del(5q)) are common in high-risk (HR) Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML); however, the gene regulatory networks that sustain these aggressive diseases are unknown. Reduced miR-146a expression in del(5q) HR-MDS/AML and miR-146a-/- hematopoietic st...
ORGANISM(S): Homo sapiens 
In vitro RNA synthesis and pull-down assay and MS spectrometry
ORGANISM(S): Homo Sapiens 
m6A is the most abundant modification of mRNA in mammals and plays an important role in human development and disease. METTL14 is a key component of m6A methyltransferase complex. The project showed that its post-translational arginine methylation can regulate the generation of m6A and the endoderm ...
ORGANISM(S): Homo Sapiens 
This project investigates the genetic basis of piroplasmosis resistance in Yunnan humped cattle through integrated transcriptomic and proteomic analyses to identify candidate genes and proteins. Proteomics datasets included the following: (1) Lancang samples: Fe16CXN_QC1--Fe16CXN_QC3(Quality testing...
ORGANISM(S): Bos Taurus Bos Indicus 
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