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MetabolomicsDistinct Metabolomic and Lipoprotein signatures in Gall Bladder Cancer patients of Black African ancestry

Gallbladder cancer (GBC) is the most common biliary tract malignancy and is often diagnosed at advanced stages, partly due to the absence of reliable biomarkers and limited understanding of its biology in African populations. This study aimed to characterize the metabolomic and lipoprotein profil...

2025-09-05 | MTBLS12944 | MetaboLights
TranscriptomicsEast Eurasian ancestry in the middle of Europe: genetic footprints of Steppe nomads in the genomes of Belarusian Lipka Tatars
Medieval era encounters of nomadic groups of the Eurasian Steppe and largely sedentary East Europeans had a variety of demographic and cultural consequences. Amongst these outcomes was the emergence of the Lipka Tatars - a Slavic-speaking Sunni-Muslim ethno-religious minority residing in modern Bela...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-82309 | biostudies-arrayexpress
ProteomicsPeptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Characterization of ancestry-linked peptide variants in disease-relevant patient tissues represents a foundational step to connect patient ancestry with molecular disease pathogenesis. Nonsynonymous single nucleotide polymorphisms (SNPs) encoding missense substitutions within tryptic peptides exhibi...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD029323 | Pride
Tmt-11 Tmt-10 Fibroid Endometrial cancer cell line Uterine leiomyoma Quantitative proteomics 
TranscriptomicsStable Patterns of Gene Expression Regulating Carbohydrate Metabolism Determined by Geographic Ancestry
Individuals of African descent in the United States suffer disproportionately from diseases with a metabolic etiology (obesity, metabolic syndrome, and diabetes), and from the pathological consequences of these disorders (hypertension and cardiovascular disease). Using a combination of genetic/geno...
ORGANISM(S): Homo sapiens 
2009-10-30 | E-GEOD-12959 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Exercise Ancestry
Transcriptome analysis of gastrocnemius muscle RNA samples from exercise and sedentary ancestries Early life and pre-conception environmental stimuli can affect adult health-related phenotypes. Exercise training is an environmental stimulus affecting many systems throughout the body and appears to a...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-40469 | biostudies-arrayexpress
TranscriptomicsGenotyping of SNP array in individuals with San ancestry in southeastern Africa
Only a few scattered groups with oral traditions of Khoe-San hunter-gatherer ancestry remain in southeastern Africa. We investigate genomic variation of remaining individuals from two South African groups with oral histories connecting them to eastern San groups, i.e., the San from Lake Chrissie and...
ORGANISM(S): Homo sapiens 
2016-09-21 | E-MTAB-5119 | biostudies-arrayexpress
GenomicsEvaluation of Ancestry Admixture among Chileans
Evaluation of Ancestry Admixture among Chileans
PRJNA391040 | ENA
GenomicsHomo sapiens strain:(GIH) Gujarati India ancestry in Houston, TX
Exome sequencing of (GIH) Gujarati India ancestry in Houston, Texas population
PRJNA59827 | ENA
GenomicsHomo sapiens strain:(ASW) African ancestry in South West US
Exome sequencing of (ASW) African ancestry in South West US population
PRJNA59835 | ENA
TranscriptomicsGenetic ancestry and natural selection drive population differences in immune responses to pathogens in humans
Individuals from different populations vary considerably in their susceptibility to immune-related diseases. To understand how genetic variation and natural selection contribute to these differences, we tested for the effects of African versus European ancestry on the transcriptional response of pri...
ORGANISM(S): Homo sapiens 
2016-09-06 | E-GEOD-81046 | biostudies-arrayexpress
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