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GenomicsNeuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
We report the application of single molecule-based sequencing technology for high-throughput genom-wide mapping of MeCP2 binding and DNA methylation in mouse brain and cerebellum respectively. We find a good correlation between MeCP2 occupancy and methyl-CpG density and depletion of MeCP2 binding at...
ORGANISM(S): Mus musculus 
2010-03-04 | E-GEOD-19786 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 269 individuals from three geographically distinct human populations to investigate copy number variation
We conducted comparative genome hybridization experiments to catalogue the common copy number variation evident between 269 individuals from three geographically distinct human populations (Yoruban, Chinese/Japanese, European) against a single reference individual.
ORGANISM(S): Homo sapiens 
2006-07-31 | E-TABM-107 | biostudies-arrayexpress
GenomicsComprehensive analysis of orphan CpG islands identifes novel promoters with conserved DNA methylation dynamics
We report the application of single molecule-based sequencing technology in combination with CXXC affinity purifcation (CAP-seq), MBD affinity purification (MAP-seq) and chromatin immunoprecipitation (ChIP-seq) to generate reciprocal methylation and chromatin modifcation maps in human and mouse. We ...
ORGANISM(S): Mus musculus 
2010-10-04 | E-GEOD-21442 | biostudies-arrayexpress
GenomicsGenome-wide maps of CFP1, RNA Polymerase II and H3K4me3 in mouse brain.
We report the application of single molecule-based sequencing technology for high-throughput mapping of CFP1, RNA polymerase II and H3K4me3 in mouse brain. By obtaining sequence from chromatin immunoprecipitated DNA, we generated genome-wide binding / chromatin-state maps for mouse brain. We find a ...
ORGANISM(S): Mus musculus 
2010-04-15 | E-GEOD-18578 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human carcinoma in situs cells from testis compared to fetal gonocytes, oogonia and cultured embryonic stem cells
Abstract: Testicular cancers in young adult men derive from an inborn precursor lesion, called carcinoma in situ (CIS) of the testis. CIS cells are believed to arise from primordial germ cells or gonocytes that fail to differentiate into the male germ cell lineage, and show a remarkable resemblance ...
ORGANISM(S): Homo sapiens 
2009-06-15 | E-TABM-488 | biostudies-arrayexpress
TranscriptomicsRNAseq analysis on mature leaf tissue of 60 individual B104 maize inbred plants grown in the field
60 plants B104 genotype. Collected in field conditions. No perturbation were applied. The general aim of our study is to prove that the same type of information coming from pooled samples of plants that were grown in controlled chambers can also be deduced from experiments in the field, using the na...
ORGANISM(S): Zea mays 
2020-08-31 | E-MTAB-8944 | biostudies-arrayexpress
no omics definedTiling path analysis to determine copy-number variation in 40 Utah/Morman and Yoruban population samples using NimbleGen technology
A copy-number variation (CNV) analysis was run on 40 CEU and YRI samples across an array set tiling across the human genome. The array contained 42 million oligos spread across 20 arrays. The final design provided 1 probe per 50bp average density across the genome.

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ORGANISM(S): Homo sapiens 
2009-04-01 | E-MTAB-40 | biostudies-arrayexpress
UnknownThe association between physiologic dead-space fraction and mortality in subjects with ARDS enrolled in a prospective multi-center clinical trial.
Not available
S-EPMC4077995 | biostudies-literature
UnknownEvaluating Muscle Mass in Survivors of Acute Respiratory Distress Syndrome: A 1-Year Multicenter Longitudinal Study.
Not available
S-EPMC6051433 | biostudies-literature
UnknownTracking Parkinson's: Study Design and Baseline Patient Data.
Not available
S-EPMC4927877 | biostudies-literature
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