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UnknownE-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271.
Not available
S-EPMC5729350 | biostudies-literature
UnknownPronounced and extensive microtubule defects in a Saccharomyces cerevisiae DIS3 mutant.
Not available
S-EPMC3367412 | biostudies-literature
TranscriptomicsTranscription profiling of mouse cartilage tumours IGFBP-3 reveals is regulated by Gli signaling in cartilage tumors.
Mice that develop benign cartilage lesions due to overexpression of Gli2 in chondrocytes developed lesions similar to chondrosarcomas when also deficient in p53. Gli2 overexpression and p53 deficiency had opposing effects on chondrocyte differentiation, but had additive effects negatively regulatin...
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15118 | biostudies-arrayexpress
UnknownA novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting.
Not available
S-EPMC302084 | biostudies-literature
UnknownIdentification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR).
Not available
S-EPMC3236341 | biostudies-literature
UnknownIdentification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions.
Not available
S-EPMC3995140 | biostudies-literature
UnknownA genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.
Not available
S-EPMC10411002 | biostudies-literature
TranscriptomicsGenome-wide localization of exosome components to active promoters and chromatin insulators in Drosophila
Chromatin insulators are functionally conserved DNA-protein complexes that are situated throughout the genome and organize independent transcriptional domains.  Previous work implicated RNA as an important cofactor in chromatin insulator activity, although the mechanisms by which RNA affects insulat...
ORGANISM(S): Drosophila melanogaster 
2013-01-29 | E-GEOD-41950 | biostudies-arrayexpress
TranscriptomicsPronounced and Extensive Microtubule Defects in a Saccharomyces cerevisiae DIS3 Mutant
The recently proposed exozyme hypothesis posits that subunits of the RNA processing exosome assemble into structurally distinct protein complexes that function in disparate cellular compartments and RNA metabolic pathways. Here, in a genetic test of this hypothesis, we examine the role of Dis3 -- a...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-01 | E-GEOD-29018 | biostudies-arrayexpress
UnknownSNP-SNP interactions in breast cancer susceptibility.
Not available
S-EPMC1522021 | biostudies-literature
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