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TranscriptomicsTranscription profiling of rat aortic rings treated with angiopoietin-1, VEGF or untreated
Specific Aims ; To identify novel transcriptional events associated with angiogenesis in VEGF and Ang-1 stimulated rat aortic rings. Our studies take advantage of the capacity of rat aortic rings to generate new vessels in collagen gels. Rat aortic rings embedded in collagen gel immediately after e...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-3355 | biostudies-arrayexpress
TranscriptomicsAlterations in skeletal muscle mRNA profile by angiopoietin-1 and angiopoietin-2
Analysis of changes in skeletal muscle myoblasts in response to over-expression of angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2). The hypothesis tested in the present study was that over-expression of Ang-1 or Ang-2 will induce the expression of pro-survival and pro-differentiation genes in skel...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-29508 | biostudies-arrayexpress
GenomicsThe role of Angiopoietin 1 in acute-on-chronic liver failure
The role of Angiopoietin 1 in acute-on-chronic liver failure
PRJNA1507394 | ENA
ProteomicsPhosphoproteomic analysis of endothelial cells treated with VEGF and Ang-1
The phosphoproteomes of bovine aortic endothelial cells (BAECs) treated with VEGF or Angiopoietin-1 for 10min were analyzed using LC-MS/MS.
ORGANISM(S): Bos taurus (Bovine) 
2016-02-09 | PXD002456 | Pride
Endothelial cells Vegf Angiopoietin-1 Phosphoproteomic 
TranscriptomicsAlterations in skeletal muscle mRNA profile by angiopoietin-1 and angiopoietin-2
Analysis of changes in skeletal muscle myoblasts in response to over-expression of angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2). The hypothesis tested in the present study was that over-expression of Ang-1 or Ang-2 will induce the expression of pro-survival and pro-differentiation genes in skel...
ORGANISM(S): Homo sapiens 
2012-05-24 | GSE29508 | GEO
TranscriptomicsTranscription profiling of human HUVECs before and after Angiopoietin stimulation
Angiopoietin-Tie2 sytem has been inplicated in both vascular quiescence and angiogenesis. It is unclear how these two opposing signals are regulated from the same receptor-mediated intracellular signal transduction. We have noticed that Tie2 localization upon Angiopoietin stimulation depends upon th...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-9677 | biostudies-arrayexpress
OtherThe role of Angiopoietin 1 in acute-on-chronic liver failure
Acute-on-chronic liver failure (ACLF) is an acute liver and multisystem failure in patients with pre-existing liver disease. A common precipitating factor for ACLF is sepsis. Our recent work shows that sepsis-ACLF is associated with loss of Angiopoietin 1 (ANG-1) and endothelial dysfunction that in ...
ORGANISM(S): Mus musculus 
2026-09-01 | GSE342343 | GEO
GenomicsBlocking the Angiopoietin-2-dependent Integrin beta-1 signaling axis abrogates small cell lung cancer invasion and metastasis
Blocking the Angiopoietin-2-dependent Integrin beta-1 signaling axis abrogates small cell lung cancer invasion and metastasis
PRJNA1091666 | ENA
UnknownAngiopoietin-1 deficiency increases tumor metastasis in mice.
Not available
S-EPMC5553747 | biostudies-literature
TranscriptomicsBlocking the Angiopoietin-2-dependent Integrin beta-1 signaling axis abrogates small cell lung cancer invasion and metastasis
Small cell lung cancer (SCLC) is the most aggressive lung cancer entity with an extremely limited therapeutic outcome. Most patients are diagnosed at an extensive stage. However, the molecular mechanisms driving SCLC invasion and metastasis remain largely elusive. We used an autochthonous SCLC mouse...
ORGANISM(S): Mus musculus 
2024-03-28 | GSE262409 | GEO
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