Sort   by:  
 Page size 
ProteomicsFA-SAT ncRNA interactome
FA-SAT is a satellite DNA sequence present and transcribed in many Bilateria species, what may anticipate a conserved and significant function in these genomes. Here we prove that in cat and human cells, FA-SAT satellite transcripts play a nuclear function at the G1 phase of the cell cycle. We ident...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Felis silvestris 
2020-03-19 | PXD010081 | Pride
Fa-sat  satellite dna  non-coding rna  apoptosis  interactome  swath-ms 
ProteomicsSecretome characterization of nucleus pulposus (NP) cells subjected to ER stress
Objective: Induction of ER stress has been shown to promote NP cell apoptosis and disc degeneration. However, little is known about its regulation by hypoxia and its contribution to extracellular matrix homeostasis. Methods: NP cells were culture under hypoxia (1% O2) and normoxia (21% O2) to asse...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-12-03 | PXD019151 | Pride
Collagens Hypoxia Er stress Nucleus pulposus Secretome 
ProteomicsA generic normalization method for proper quantification in untargeted proteomics screening
The label-free quantitative mass spectrometry methods, in particular the SWATH-MS approach, have gained popularity and became a powerful technique for comparison of large datasets. In the present work, it is introduced the use of recombinant proteins as internal standards for untargeted label-free m...
ORGANISM(S): Aequorea victoria Homo sapiens (Human) Escherichia coli Rattus norvegicus (Rat) 
2019-08-19 | PXD009068 | Pride
Internal standard Data normalization Biofluids Proteomics screening Swath-ms 
ProteomicsIntracellular and extracellular proteome characterization of virulent and avirulent Bursaphelenchus xylophilus isolates
The pinewood nematode (PWN), Bursaphelenchus xylophilu (Bx) s, one of the most serious forest pests, worldwide, is considered the causal agent of the pine wilt disease (PWD). The main host species belong to the genus Pinus and a variation in the susceptibility of several pine species to PWN infectio...
ORGANISM(S): Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides xylophilus) cellular organisms 
2022-01-13 | PXD029377 | Pride
Proteomics Intracellular proteome  extracellular proteome  bursaphelenchus xylophilus Avirulent isolate Virulent isolate Pinewood nematode 
ProteomicsCx43-interaction network in the heart
The main objective of the present report was to unravel the Cx43-interaction network in the heart, and to establish the impact of heart ischemia and I/R upon these interactions. In order to characterize the cardiac Cx43 interactome under ischemia and I/R, a quantitative proteomic analysis was perfor...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-09-09 | PXD002331 | Pride
Connexin43  interactome  cardiomyocytes  ap-swath 
ProteomicsNew insights on sperm function in male infertility of unknown origin: proteomics characterization
The global trend on (male)infertility is concerning and the unidentifiable causes in half of the cases demands a better understanding of the molecular, biochemical and metabolic mechanisms as well as the identification of external and internal factors operating behind it, that might help to explain ...
ORGANISM(S): Homo sapiens (Human) 
2024-02-28 | PXD040292 | Pride
Xxxxxxidiopathic male infertility  unexplained male infertility  sperm function  sperm proteomics 
ProteomicsBursaphelenchus xylophilus secretome under Pinus pinaster and P. pinea stimuli
The pinewood nematode, Bursaphelenchus xylophilus, the pine wilt disease's causal agent, is a migratory endoparasitic nematode skilled to feed on pine tissues and on fungi that colonize the trees. In order to study B. xylophilus secretomes under the stimulus of pine species with different susceptibi...
ORGANISM(S): Bursaphelenchus xylophilus (Pinewood nematode worm) (Aphelenchoides xylophilus) 
2021-04-27 | PXD024011 | Pride
Pinus pinaster Swath-ms Bursaphelenchus xylophilus P. pinea Secretome 
ProteomicsProteomics characterization of Coelomic epithelium (CE) of the starfish Marthasterias glacialis
Coelomic epithelium (CE), or coelothelium, is a mesodermal-derived tissue lining coelomic cavities and enveloping inner organs in all coelomates, including vertebrates, where it forms both peritoneum and pericardium, as well as pleura, in mammals. Due to its histogenetic potential, CE is considered ...
ORGANISM(S): Marthasterias glacialis (Spiny starfish) 
2023-01-24 | PXD027009 | Pride
Swath-ms  coelomic epithelium  starfish  marthasterias glacialis  regeneration 
ProteomicsInfluence of substrate stiffness on the proteome of undifferentiated human umbilical cord matrix mesenchymal stem/stromal cells (hUCM-MSCs)
Cells sense the biophysical properties of the surrounding microenvironment. In particular, the stiffness of the extracellular milieu can be interrogated by cells and integrated through mechanotransduction. Many cellular processes (like proliferation, migration, or differentiation) depend on the mech...
ORGANISM(S): Homo sapiens (Human) 
2020-07-20 | PXD017674 | Pride
Mechanotransduction  cytoskeleton  mscs  proteomics  swath-ms 
ProteomicsMultiomic approaches for thyroid cancer diagnosis
Thyroid cancer is a common endocrine malignancy; however, its diagnosis is not straightforward. The current gold standard for diagnosing thyroid cancer is fine needle aspiration biopsy (FNAB), but when cytological analysis does not provide viable results or samples belong to less defined categories ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035583 | Pride
Mixomics Tissue Swath-ms Proteomics Thyroid cancer Biomarkers 
Sort   by:  
 Page size