Sort   by:  
 Page size 
This model is based on: Reinforcement learning-based control of tumor growth under anti-angiogenic therapy Authors: Parisa Yazdjerdi, Nader Meskin, Mohammad Al-Naemi, Ala-Eddin Al Moustafa, Levente Kovacs Abstract: Background and objectives: In recent decades, cancer has become one of the most fata...
2024-09-02 | BIOMD0000000821 | BioModels
Anti-angiogenic anticancer therapies possess immune-stimulatory properties by counteracting pro-angiogenic molecular mechanisms. We report that tumor endothelial cells ubiquitously overexpress and secrete the intermediate filament protein vimentin through type III unconventional mechanisms. Extracel...
ORGANISM(S): Homo sapiens (Human) 
2022-03-29 | PXD024426 | Pride
Kallikrein-related peptidase 3 (KLK3, also known as prostate-specific antigen, PSA) is a chymotrypsin-like kallikrein that has been shown to have anti-angiogenic properties. KLK3 expression in prostate cancer is associated with low microvessel density. We have previously shown in a human umbilical v...
ORGANISM(S): Homo sapiens 
Three-dimensional CRISPR screening reveals epigenetic interaction with anti-angiogenic therapy
This is a spatially averaged multiscale mathematical model of tumor angiogenesis. The model describes the dynamics of VEGF, Ang1, Ang2, and PDGF, coupled with those of mature and immature endothelial cells and pericyte cells.
2019-11-13 | MODEL1911130007 | BioModels
RNA sequencing of blood-brain barrier (BBB) microvessels from mice with orthotopic GBM showing the benefit of triple therapy combining anti-immune checkpoint therapy with dual-anti angiogenic therapy.
Sort   by:  
 Page size