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TranscriptomicsSynergistic anti-tumor activity by association of MEK and PI3K/mTOR blockade with TRAIL in human melanoma
Combining direct anti-tumor effects with targeting of tumor microenvironment is an attractive strategy that may lead to more effective therapies for advanced melanoma. Here, we tested whether association of TRAIL with co-targeting of MEK and PI3K/mTOR, or with MEK blockade, could have synergistic a...
ORGANISM(S): Homo sapiens 
2014-10-08 | E-GEOD-55050 | biostudies-arrayexpress
UnknownDevelopment of a prediction system for anti-tuberculosis drug-induced liver injury in Japanese patients.
Not available
S-EPMC4917605 | biostudies-literature
TranscriptomicsSynergistic anti-tumor activity by association of MEK and PI3K/mTOR blockade with TRAIL in human melanoma
Combining direct anti-tumor effects with targeting of tumor microenvironment is an attractive strategy that may lead to more effective therapies for advanced melanoma. Here, we tested whether association of TRAIL with co-targeting of MEK and PI3K/mTOR, or with MEK blockade, could have synergistic an...
ORGANISM(S): Homo sapiens 
2014-10-08 | GSE55050 | GEO
ProteomicsLC-MS characterization of anti-PD-L1 and CXCR4 bispecific nanobodies
Antibodies and derivative drugs targeting immune checkpoints have been approved for the treatment of several malignancies, but there are fewer responses in patients with pancreatic cancer. Here, we designed a nanobody molecule with bi-targeting on PD-L1 and CXCR4, as both targets are overexpressed i...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037102 | Pride
Nanobody Lc-ms Bispecific Protein Complete mw 
GenomicsAnti-IgE Effect of Naturally Occurring Arctigenin on Food Allergy Association with a Distinct Transcriptome Profile
Anti-IgE Effect of Naturally Occurring Arctigenin on Food Allergy Association with a Distinct Transcriptome Profile
PRJNA759623 | ENA
MetabolomicsA metabolomic study of urinary changes in type 2 diabetes in human compared to the control group
Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target tissues. There are an estimated 150 million affected individuals worldwide, of whom a large proportion remains undiagnosed because of a lack of specific symptoms early in ...
2012-02-14 | MTBLS1 | MetaboLights
UnknownCancer association as a risk factor for anti-HMGCR antibody-positive myopathy.
Not available
S-EPMC5056647 | biostudies-literature
UnknownAssociation between anti-endothelial antigen antibodies and allograft rejection in kidney transplantation.
Not available
S-EPMC10561590 | biostudies-literature
GenomicsThe photoreceptor chaperone FHY1 has an independent role in gene modulation and plant development under far-red light [ChIP-seq]
To incorporate the far-red light (FR) signal into a strategy for optimizing plant growth, FAR-RED ELONGATED HYPOCOTYL1 (FHY1) mediates the nuclear translocation of the FR photoreceptor phytochrome A (phyA) and facilitates the association of phyA with the promoters of numerous associated genes crucia...
ORGANISM(S): Arabidopsis thaliana 
2014-08-04 | E-GEOD-58083 | biostudies-arrayexpress
UnknownAssociation between anti-SSSCA1 antibodies and cancer in systemic sclerosis.
Not available
S-EPMC10321112 | biostudies-literature
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