Sort   by:  
 Page size 
MetabolomicsAbsolute quantification of serum cytokines and metabolome reveals the glycylproline regulating antibody-fading in convalescent COVID-19 patients

The COVID-19 pandemic has incurred tremendous costs worldwide and is still threatening public health in the 'new normal'. The association between neutralizing antibody levels and metabolic alterations in convalescent patients with COVID-19 is still poorly understood. In the present work, we condu...

2024-08-26 | MTBLS3305 | MetaboLights
MetabolomicsB cell expression of the enzyme PexRAP, an intermediary in ether lipid biosynthesis, promotes antibody responses and germinal center size.

The qualities of antibody (Ab) responses provided by B lymphocytes and their plasma cell (PC) descendants are crucial facets of responses to vaccines and microbes. Metabolic processes and products regulate aspects of B cell proliferation and differentiation into germinal center (GC) and PC states...

2026-04-13 | MTBLS13880 | MetaboLights
ProteomicsBenchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
Antibodies are immune glycoproteins that represent a crucial part of the adaptive immune system as they mediate broad protection against viruses, bacteria, and cancer. Moreover, antibodies may serve as a unique source of information on past and current physiological and pathological events in the hu...
ORGANISM(S): Homo sapiens (Human) 
2024-06-04 | PXD046237 | Pride
Human Lc-msms Plasma Antibody 
ProteomicsAntibody microarray profiling of pancreatic cancer using 12 urine samples
Antibody microarray based profiling of twelve urine samples.
3 healthy female
3 heatlhy male
3 female with pancreatic cancer
3 male with pancreatic cancer
ORGANISM(S): Homo sapiens 
2012-05-03 | E-MEXP-3006 | biostudies-arrayexpress
MetabolomicsMetabolomic/lipidomic profiling of COVID-19 and individual response to tocilizumab
The current pandemic emergence of novel coronavirus disease (COVID-19) poses a relevant threat to global health. SARS-CoV-2 infection is characterized by a wide range of clinical manifestations, ranging from absence of symptoms to severe forms that need intensive care treatment. Here, plasma-EDTA sa...
2022-02-21 | MTBLS2336 | MetaboLights
ProteomicsProfiling proteome-scale antibody responses to M. tuberculosis
This SuperSeries is composed of the following subset Series: GSE30721: Profiling proteome-scale antibody responses to M. tuberculosis proteins in sera of macaques infected with M. tuberculosis GSE30722: Profiling proteome-scale antibody responses to M. tuberculosis proteins in TB suspect's sera Refe...
ORGANISM(S): Homo sapiens 
2012-07-05 | E-GEOD-31368 | biostudies-arrayexpress
ProteomicsProfiling antibody function on antigen arrays
Humoral immune responses are traditionally characterized by determining the presence and quality of antibodies specific for certain antigens. Arraying of large numbers of antigens allows the parallel measurement of antibodies, generating patterns called antibody profiles. Functional characterization...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-12943 | biostudies-arrayexpress
GenomicsHigh-throughput profiling of antigen-specific antibody secreting cells using an antibody secretion trap (TRAPnSeq)
High-throughput profiling of antigen-specific antibody secreting cells using an antibody secretion trap (TRAPnSeq)
PRJNA976400 | ENA
MetabolomicsMetabolic profiling reveals CAD as a central metabolic signaling node
LC MS metabolite profiling and carbon tracing were used to show that the pyrimidine synthesis enzyme CAD regulates glycolysis and branching into pentose phosphate and serine synthesis pathways to support cancer cell proliferation.
2026-02-03 | MTBLS13498 | MetaboLights
ProteomicsDirect comparison of the hinge-cleaving proteases IgdE and BdpK for LC-MS based IgG1 clonal profiling
Human antibodies are heterogeneous molecules, primarily due to clonal sequence variations. Analytical techniques to assess antibody levels quantitatively, like ELISA assays, lack the power to determine abundances at the clonal level. Recently, we introduced an LC-MS-based approach that can distingui...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-17 | MSV000092676 | MassIVE
Sort   by:  
 Page size