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ProteomicsAbsolute quantification of peptides from TIM23 or PINK1-3HA using AQUA peptides
To quantify TIM23 and PINK1-3HA in the immunoprecipitates, control or PINK1-3HA expressing HeLa cells were treated with CCCP and subjected to immunoprecipitation with anti-HA antibody bound to magnetic beads. After spiked with 200 fmol stable isotope-labeled AQUA peptides (Cosmo Bio Co Ltd) as stand...
ORGANISM(S): Homo Sapiens (human) 
2023-04-07 | PXD041244 | JPOST Repository
TranscriptomicsTranscription profiling of human osteoblasts differentiated from human mesenchymal stem cells and treated with three bioactive peptides
Effects of bioactive peptides IPP(Ile-Pro-Pro), VPP (Val-Pro-Pro), and LKP(Leu-Lys-Pro) on gene expression of osteoblast differentiated from human mesenchymal stem cells. Experimental design types: compound treatment and augmented reference design.
ORGANISM(S): Homo sapiens 
2008-01-23 | E-MEXP-885 | biostudies-arrayexpress
MetabolomicsMetabolomic Profile of Diet-Induced Obesity Mice in Response to Human and Small Humanin-like Peptide 2 Treatment

INTRODUCTION: The mitochondrial-derived peptides (MDPs) are a novel group of natural occurring peptides that have important signaling functions and biological activity. Both humanin and small-humanin-like peptide 2 (SHLP2) have been reported to act as insulin sensitizers and modu...

2019-06-21 | MTBLS159 | MetaboLights
ProteomicsStoichiometry of Nucleosome Remodelling and Deacetylase (NuRD) complex
The Nucleosome Remodeling and Deacetylase (NuRD) complex is essential for development in complex animals but has been refractory to detailed analysis because of its low abundance and resistance to recombinant production. As part of a larger project, absolute quantification using isotopically-labelle...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2021-01-08 | PXD010110 | Pride
Quantitative ms Nurd Aqua 
TranscriptomicsDifferent gene expressions in root tips between CLE10 and CLE25 treatment
Cell–cell communication is critical for tissue and organ development. In plants, secretory CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides function as intercellular signaling molecules in various aspects of tissue development. However, little is known about intracellular signaling pathways...
ORGANISM(S): Arabidopsis thaliana 
2010-09-03 | E-GEOD-19978 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of bacteria challenged with antimicrobial peptides of plant origin
Effect of NCR247 and NCR335 on S. meliloti transcriptosome using Solid4 sequencer S. meliloti 1021 strain was treated by 10 mg/L synthetised NCR247 or NCR335 peptides and gene expression were measured after 10 and 30 minutes
ORGANISM(S): Sinorhizobium meliloti 1021 
2013-05-30 | E-GEOD-47447 | biostudies-arrayexpress
ProteomicsAbsolute quantification and copy number estimation of the TNF-RSC members in A549 cells
Determine the copy number per cell of the TNF-RSC members in A549 cells using targeted proteomics (PRM) combined with spike-in of known amounts of reference peptides.
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD019959 | Pride
Aqua Prm Copy number Tnf-rsc 
TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
ProteomicsMOUSE CSF Parallel Reaction Monitoring
MOUSE CSF PRM Mecp2 - 20 samples with AQUA standards
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD029835 | Pride
Mouse Prm Csf 
ProteomicsAge-related cleavages of crystallins in human lens cortical fibre cells generate a plethora of low molecular weight peptides and cross-linked crystallin complexes
A large variety of low molecular weight (LMW) peptides, derived from the breakdown of crystallins, have been reported in middle to old age human lenses. The proliferation of these LMW peptides coincides with the earliest stages of cataract formation, suggesting that the protein cleavages involved ma...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000081536 | MassIVE
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