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MetabolomicsTissue metabolites in diffuse glioma and their modulations by IDH1 mutation, histology, and treatment
The discovery of the oncometabolite 2-hydroxyglutarate in isocitrate dehydrogenase 1-mutated (IDH1-mutated) tumor entities affirmed the role of metabolism in cancer. However, large databases with tissue metabolites that are modulated by IDH1 mutation remain an area of development. Here, we present a...
2022-09-07 | MTBLS3873 | MetaboLights
TranscriptomicsGene expression profiling of archival tongue carcinoma and normal tongue tissue
This SuperSeries is composed of the following subset Series: GSE34105: Gene expression profiling of archival tongue carcinoma and normal tongue tissue (all samples) GSE34106: Gene expression profiling of archival tongue carcinoma and normal tongue tissue (subset) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-34115 | biostudies-arrayexpress
TranscriptomicsAutomated array-CGH optimized for archival formalin-fixed, paraffin-embedded tumor material
BACKGROUND: Array Comparative Genomic Hybridization (aCGH) is a rapidly evolving technology that still lacks complete standardization. Yet, it is of great importance to obtain robust and reproducible data to enable meaningful multiple hybridization comparisons. Special difficulties arise when aCGH i...
ORGANISM(S): Homo sapiens 
2010-06-12 | E-GEOD-7122 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of archival tongue carcinoma and normal tongue tissue (subset)
RNA extracted from 78 FFPE tongue samples, 62 tongue carcinomas and 16 non-malignant controls, were succesfully analysed using the whole genome DASL array to obtain gene expression profiles. Gene expression profiles were used to identify differentially expressed genes with the ultimate goal of findi...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-34106 | biostudies-arrayexpress
TranscriptomicsA Comparison of HEEBO Microarray and 3'-end Sequencing for Expression Quantification (3SEQ) (Archival Tumor Samples)
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET). Consequently, microarrays cannot be effectively utilized to perform gene expression profiling on the vast ...
ORGANISM(S): Homo sapiens 
2010-03-25 | E-GEOD-18209 | biostudies-arrayexpress
TranscriptomicsHigh Resolution Copy Number Analysis of Paraffin Embedded Archival Tissue Using SNP BeadArrays
High density SNP microarrays provide insight into the genomic events that occur in diseases like cancer by their capability to measure both LOH and genomic copy numbers. Where currently available methods are restricted to the use of fresh frozen tissue, we now describe the design and validation of c...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-GEOD-5347 | biostudies-arrayexpress
GenomicsAccurate genome-wide germline DNA profiling from decade-old archival tissue specimen
Accurate genome-wide germline DNA profiling from decade-old archival tissue specimen
PRJNA823474 | ENA
GenomicsAccurate genome-wide germline DNA profiling from decade-old archival tissue specimen
Accurate genome-wide germline DNA profiling from decade-old archival tissue specimen
PRJNA823475 | ENA
TranscriptomicsGene expression profiling of archival tongue carcinoma and normal tongue tissue (all samples)
RNA extracted from 78 FFPE tongue samples, 62 tongue carcinomas and 16 non-malignant controls, were succesfully analysed using the whole genome DASL array to obtain gene expression profiles. Gene expression profiles were used to identify differentially expressed genes with the ultimate goal of findi...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-34105 | biostudies-arrayexpress
TranscriptomicsClinical relevance of DNA microarray analyses using archival formalin-fixed paraffin-embedded breast cancer specimens
This SuperSeries is composed of the following subset Series: GSE23384: Gene profiling using archival formalin-fixed paraffin-embedded breast cancer specimens can generate informative microarray data: A comparison with matched fresh fine needle aspiration biopsy samples (FFPE samples) GSE23385: Gene ...
ORGANISM(S): Homo sapiens 
2011-06-22 | E-GEOD-23386 | biostudies-arrayexpress
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