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ProteomicsThe ubiquitin ligase Ariadne-1 regulates NSF for neurotransmitter release
The aim of the present project was to identify putative substrates of Ariadne-1 (Ari-1), an essential E3 ubiquitin-ligase, in Drosophila heads. For that purpose we combined an in vivo ubiquitin biotinylation strategy termed bioUb with label free mass spectrometry analysis. In brief, BioUb strategy r...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-02-09 | PXD022701 | Pride
Synapse E3 ubiquitin ligase Neurotransmitter release Ubiquitination Ariadne-1 Drosophila Nsf 
UnknownThe ubiquitin ligase Ariadne-1 regulates neurotransmitter release via ubiquitination of NSF.
Not available
S-EPMC7960542 | biostudies-literature
ProteomicsQuantitative XL-MS Analysis of HHARI in the presence or absence of 4EHP
RING-Between-RING (RBR) E3 ligases mediate ubiquitin transfer through an obligate E3- ubiquitin thioester intermediately prior to substrate ubiquitination. While RBRs share a conserved catalytic module, substrate recruitment mechanisms remain enigmatic and the relevant domains have yet to be identi...
ORGANISM(S): Homo Sapiens 
PXD030871 | panorama
UnknownSalvianic acid A promotes osteogenic differentiation of bone marrow mesenchymal stem cells in senile osteoporosis through bromodomain-containing protein 4/Ariadne RBR E3 ubiquitin-protein ligase 1/Rubicon axis.
Not available
S-EPMC12266271 | biostudies-literature
UnknownCoupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.
Not available
S-EPMC6393609 | biostudies-literature
UnknownEffectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy: study protocol of a cluster randomized clinical trial (Multi-PAP project).
Not available
S-EPMC5406997 | biostudies-literature
UnknownAriadne: a database search engine for identification and chemical analysis of RNA using tandem mass spectrometry data.
Not available
S-EPMC2665244 | biostudies-literature
ProteomicsCullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain
RING-Between-RING (RBR) E3 ligases mediate ubiquitin transfer through an obligate E3- ubiquitin thioester intermediately prior to substrate ubiquitination. While RBRs share a conserved catalytic module, substrate recruitment mechanisms remain enigmatic and the relevant domains have yet to be identi...
ORGANISM(S): Homo sapiens (Human) 
2023-05-24 | PXD030849 | Pride
Kojak Cross-linking mass spectrometry Proxl Skyline Cullin Xl-ms Hhari Ubiquitin Rbr E3 ligase 
UnknownAriadne: synthetic long read deconvolution using assembly graphs.
Not available
S-EPMC10463629 | biostudies-literature
UnknownManagement of heart failure with reduced ejection fraction in Europe: design of the ARIADNE registry.
Not available
S-EPMC7160498 | biostudies-literature
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