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The ARID1A subunit of the SWI/SNF chromatin remodelling complex is one of the most frequently mutated tumour suppressors. Here, a degron system is applied to detect rapid loss of chromatin accessibility at thousands of loci that frequently include binding sites for pluripotency transcription factors...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD021636 | Pride
The ARID1A subunit of the SWI/SNF chromatin remodelling complex is one of the most frequently mutated tumour suppressors. Here, a degron system is applied to detect rapid loss of chromatin accessibility at thousands of loci that frequently include binding sites for pluripotency transcription factors...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD021624 | Pride
The ARID1A subunit of the SWI/SNF chromatin remodelling complex is one of the most frequently mutated tumour suppressors. Here, a degron system is applied to detect rapid loss of chromatin accessibility at thousands of loci that frequently include binding sites for pluripotency transcription factors...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD021631 | Pride
The ARID1A subunit of the SWI/SNF chromatin remodelling complex is one of the most frequently mutated tumour suppressors. Here, a degron system is applied to detect rapid loss of chromatin accessibility at thousands of loci that frequently include binding sites for pluripotency transcription factors...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD021623 | Pride
The ARID1A subunit of the SWI/SNF chromatin remodelling complex is one of the most frequently mutated tumour suppressors. Here, a degron system is applied to detect rapid loss of chromatin accessibility at thousands of loci that frequently include binding sites for pluripotency transcription factors...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD021824 | Pride
Differentially expressed genes following ARID1A depletion
AT-rich interactive domain-containing protein 1A (ARID1A), a SWI/SNF chromatin remodeling complex subunit, is frequently mutated across various cancer entities. ARID1A contributes to DNA damage response pathways, and we previously reported that ARID1A loss is associated with mutational signatures li...
ORGANISM(S): Homo sapiens (Human) 
2025-04-08 | PXD046159 | Pride
AT-rich interactive domain-containing protein 1A (ARID1A), a SWI/SNF chromatin remodeling complex subunit, is frequently mutated across various cancer entities. ARID1A contributes to DNA damage response pathways, and we previously reported that ARID1A loss is associated with mutational signatures li...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD047225 | Pride
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for EP300 dependent activation and repression of transcription.
ARID1A depletion Raw sequence reads
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