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ProteomicsMALDI-IMS combined with shotgun proteomics identify and localize new factors in male infertility
Spermatogenesis is a complex multi-step process involving intricate interactions between different cell types in the male testis. Disruption of these interactions results in infertility. Combination of shotgun tissue proteomics with MALDI imaging mass spectrometry is markedly potent in revealing top...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-07 | PXD022870 | Pride
Maldi imaging mass spectrometry Mouse Estrogen Arom+ Male infertility Testis 
ProteomicsArchitecture and structural dynamics of the AROM complex
Cross-linking/mass spectrometry was used to study inter-domain interactions in the multifunctional AROM complex from Chaetomium thermophilum.
ORGANISM(S): Chaetomium thermophilum 
2019-10-02 | PXD010479 | Pride
Chemical cross-linking  dss  structural proteomics  hybrid structural biology 
ProteomicsLiver lipid metabolism is altered by increased circulating estrogen to androgen ratio in the liver of male mouse
Estrogens are suggested to lower the risk of developing metabolic syndrome in both sexes. In this study, we investigated how the increased circulating estrogen-to-androgen ratio (E/A) alters liver lipid metabolism in males. Mice expressing human aromatase enzyme (AROM+ mice), and thus having high ci...
ORGANISM(S): Mus musculus (Mouse) 
2015-12-23 | PXD002025 | Pride
Aromatase Phospholipid Label free quantitative proteomics Metabolomics Liver Male mouse 
TranscriptomicsMicroarray analysis of the testis from the aromatase overexpression transgenic and WT mice
To futher find the gene expression due to the aromatase overexpression in the mouse testis,we have employ whole genome microarray expression profiling as a discovery platform to identify genes compared to the wild type mice. The testes were taken from 5 month old aromatase overexpression mice and ...
ORGANISM(S): Mus musculus 
2014-04-18 | E-GEOD-55254 | biostudies-arrayexpress
UnknownThe effects of myofascial induction therapy in survivors of head and neck cancer: a randomized, controlled clinical trial.
Not available
S-EPMC9758021 | biostudies-literature
UnknownMolecular Characterization and Expression of Cytochrome P450 Aromatase in Atlantic Croaker Brain: Regulation by Antioxidant Status and Nitric Oxide Synthase During Hypoxia Stress.
Not available
S-EPMC8381199 | biostudies-literature
UnknownTestosterone complex and non-steroidal ligands of human aromatase.
Not available
S-EPMC5997392 | biostudies-literature
UnknownMo-catalyzed asymmetric olefin metathesis in target-oriented synthesis: enantioselective synthesis of (+)-africanol.
Not available
S-EPMC395989 | biostudies-literature
UnknownDevelopment of benzofuran-derived sulfamates as dual aromatase-steroid sulfatase inhibitors (DASIs): design, synthesis and biological evaluation.
Not available
S-EPMC11792066 | biostudies-literature
UnknownIncreased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Not available
S-EPMC5668598 | biostudies-literature
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