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UnknownSESOTHO trial ("Switch Either near Suppression Or THOusand") - switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa.
Not available
S-EPMC5810070 | biostudies-literature
TranscriptomicsArabidopsis tissue atlas
We used state of the art mass spectrometry and RNA sequencing (RNA-Seq) to provide the first integrated proteomic, phosphoproteomic and transcriptomic atlas of Arabidopsis. For this we measured 30 different Arabidopsis tissues from adult plants, seedlings, callus and cell culture samples to an avera...
ORGANISM(S): Arabidopsis thaliana 
2020-01-10 | E-MTAB-7978 | biostudies-arrayexpress
TranscriptomicsComparative analysis of genomic features of human HIV-1 infection and primate models of SIV infection
High levels of HIV-1 replication during the chronic phase of infection are usually associated with rapid disease progression (RP). However, a minority of HIV-infected individuals remain asymptomatic and show persistently high CD4+ T cell counts despite high viremia for many years (viremic non progre...
ORGANISM(S): Homo sapiens 
2011-06-03 | E-GEOD-28128 | biostudies-arrayexpress
ProteomicsTop-down proteome of de-fatted Bos taurus milk from an animal with clinical mastitis
Quarter-milk samples were collected from a cow with clinical mastitis on day 13 and day 16 postpartum. Milk was collected from a clinical quarter with signs of abnormality (i.e., flakes, clots, blood) and one normal quarter of the same animal. Milk samples were processed with the MPLEx protocol (ht...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) 
2022-02-09 | MSV000088805 | MassIVE
ProteomicsMonitoring mAb proteoforms in mouse plasma using an automated immunocapture combined with top-down and middle-down mass spectrometry
We propose here a workflow based on an automated immunocapture followed by top-down and middle-down LC-MS/MS approaches to characterize mAb proteoforms spiked in mouse plasma. We demonstrate the applicability of our workflow on a large concentration range using pembrolizumab as a model. We also comp...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2024-08-27 | PXD040896 | Pride
Immunocapture Monoclonal antibody Proteoforms Middle-down mass spectrometry Top-down mass spectrometry 
UnknownGigaSOM.jl: High-performance clustering and visualization of huge cytometry datasets.
Not available
S-EPMC7672468 | biostudies-literature
UnknownPathological Role of Anti-CD4 Antibodies in HIV-Infected Immunologic Nonresponders Receiving Virus-Suppressive Antiretroviral Therapy.
Not available
S-EPMC5853506 | biostudies-literature
ProteomicsIntact extracellular vesicle cross-linking on vesicles derived from MDA-MB-231 and LM2 cells
The development of any pharmaceutical requires characterization of the compound, usually be several techniques. Therefore, characterizing the protein content and biochemical state of EVs is of great importance for their useif they are to be used as biopharmaceuticals. Structural characterization of ...
ORGANISM(S): Homo sapiens (Human) 
2022-11-08 | PXD029591 | Pride
Tnbc Evs Xl-ms Structural proteomics Cx-ms 
Genomicsena-DATASET-JKUL-22-06-2017-13:28:22:098-263 - samples
We present targeted NGS panel data from 170 samples that were processed using the TruSightTM Cancer (TSC) panel (Illumina, San Diego, CA, USA), which targets 94 genes and 284 SNPs associated with a predisposition towards cancer. The samples are enriched for CNVs in the genes of interest. All CNVs ha...
EGAD00001003400 | EGA
GenomicsCNV detection in targeted NGS panel data
The aim of this study was to compare copy-number-variation (CNV) detection methods for targeted NGS panel data in a clinical diagnostic setting. We present targeted NGS panel data from 170 samples that were processed using the TruSight(TM) Cancer (TSC) panel (Illumina, San Diego, CA, USA), which tar...
EGAS00001002481 | EGA
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