Sort   by:  
 Page size 
Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programs around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline based drugs is becoming critical. ...
ORGANISM(S): Plasmodium falciparum 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Plasmodium falciparum 
In the context of artemisinin resistance, the objective of the project was to evaluate the role of apicoplast and mitochondrion pathways during the parasite quiescent state induced by dihydroartemisinin (DHA) treatment. We analysed the proteome of artemisinin-resistant parasites in two conditions: a...
ORGANISM(S): Plasmodium falciparum 
2025-05-06 | PXD048354 | Pride

The emergence of multi-drug resistant Plasmodium falciparum underscores the urgent need for new antimalarial therapies. SC83288, a novel chemical entity, is highly effective against P. falciparum both in vivo and in vitro, including strains resistant to artemisinin and partner drugs. Here, we sho...

2026-02-16 | MTBLS13911 | MetaboLights
This SuperSeries is composed of the following subset Series: GSE25878: Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription (expression) GSE25879: Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern...
ORGANISM(S): Plasmodium falciparum 
Artemisinin (ART)-resistant Plasmodium falciparum (Pf) threatens global malaria control. Resistance, driven by mutations in Pfk13, is multifaceted but quiescence plays a central role. Epigenetic regulation may contribute, given that only a percentage of parasites survive a pulse of the active drug m...
ORGANISM(S): Plasmodium falciparum 
2024-06-22 | PXD043747 | Pride
Sort   by:  
 Page size