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TranscriptomicsASF1
Transcription profiling by array of HeLa cells after the knock-down of ASF1 (ASF1a & ASF1b) by siRNA compared to non-targeting control siRNA
ORGANISM(S): Homo sapiens 
2014-01-14 | E-MTAB-1909 | biostudies-arrayexpress
GenomicsGenome-wide targets of conserved histone chaperone Asf1 in budding yeast
Asf1, through its histone chaperone activity, helps chromatin closing/opening during DNA replication, repair, recombination and transcription. Despite extensive research on Asf1-mediated physiological functions, a genome-wide localization map is lacking, limiting our knowledge of chromosomal feature...
ORGANISM(S): Saccharomyces cerevisiae 
2014-07-30 | E-GEOD-40717 | biostudies-arrayexpress
TranscriptomicsRNA-seq of HeLa cells to investigate regulation of replicative histone RNA metabolism by the histone chaperone ASF1
Histones are the protein components of the basic unit of chromatin, the core particle of the nucleosome. They play a central role in defining chromatin states associated with distinct cell fates and are classified into replicative and non-replicative/replacement histone variants. While the latter do...
ORGANISM(S): Homo sapiens 
2023-11-29 | E-MTAB-12501 | biostudies-arrayexpress
ProteomicsASF1 acts with RIF1 to promote DNA end-joining in BRCA1 deficient cells
RIF1 acts downstream of 53BP1 to coordinate DNA double strand break repair pathway choice between non-homologous end joining (NHEJ) and homologous recombination (HR). Here we identified ASF1 as an endogenous RIF1-associated protein. We showed that ASF1 forms complex with RIF1 and regulates RIF1-depe...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD027727 | Pride
Rif1 Tap-ms Asf1 Interactome 
GenomicsHistone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis
Histone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis
PRJNA779072 | ENA
TranscriptomicsRNAi profiling by array of human U-2-OS osteosarcoma cells with knockdown of Asf1a and Asf1b
We used RNAi to knock-down the two isoforms of Asf1, Asf1a and Asf1b, in human U-2-OS osteosarcoma cells. We obtained two replicates each with siRNAs against Asf1a, Asf1b, combined siRNAs against both isoforms, and two control samples. For these samples, we measured genome-wide transcription levels ...
ORGANISM(S): Homo sapiens 
2011-01-01 | E-MEXP-2671 | biostudies-arrayexpress
TranscriptomicsAsf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci
This SuperSeries is composed of the following subset Series: GSE25597: Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to promote nucleosome occupancy at heterochromatic loci (ChIP-chip) GSE25598: Asf1/HIRA facilitate global histone deacetylation and associate with HP1 to pr...
ORGANISM(S): Schizosaccharomyces pombe 
2011-01-07 | E-GEOD-25605 | biostudies-arrayexpress
GenomicsBisulfite sequencing of Sordaria macrospora wild type and asf1 mutant
Bisulfite sequencing of Sordaria macrospora wild type and asf1 mutant
PRJNA454909 | ENA
ProteomicsHistone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis
Histone chaperones and chromatin remodelers control nucleosome dynamics, essential for transcription, replication, and DNA repair. The histone chaperone Anti-Silencing Factor 1 (ASF1) plays a central role in facilitating CAF-1-mediated replication-dependent H3.1 deposition and HIRA-mediated replicat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-10-31 | PXD035578 | Pride
Arabidopsis Lcms Proteomics 
GenomicsHistone H4 acetylation in wild-type, ASF1, SET2 and ASF1 SET2 deletion yeast strains
ChIP-on chip assays to measure the change in histone acetylation over the yeast genome, in ASF1, SET2 and ASF1 SET2 deletion yeast strains compared to the wild-type control. ChIPs of AcH4 from wild-type, ASF1, SET2 and ASF1 SET2 deletion yeast strains were normalized to the H3 enrichment.
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-25 | GSE28098 | GEO
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