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We determined the gene expression profiles of murine melan-a melanocytes treated with ASP or alpha-MSH over a 4 days time course using genome-wide oligonucleotide microarrays. As expected, the gene expression patterns emphasized the opposing effects of the 2 ligands, and there were significant reduc...
ORGANISM(S): Mus musculus 
BIK1 is a central regulator of signaling downstream of the activation of patter recognition receptors and may represent a functional link between pattern- and effector- triggered immunity in plants. Among myriad BIK1 substrates are several intracellular immune receptors. This project aims to map BIK...
ORGANISM(S): Escherichia coli 
2026-03-02 | PXD065397 | Pride
Plasmodium falciparum pathology is driven by the accumulation of parasite-infected erythrocytes in blood capillaries. We demonstrate a novel approach to identify pathogen-specific human monoclonal antibodies directly from plasma, combining mass-spectrometry analysis of antigen-purified polyclonal pl...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD064525 | Pride
This model features the phosphorylation of rat brain neuronal NOS expressed in E. coli or Sf9 cells, which leads to a decrease in Vmax of the phosphorylated enzyme, with little change of both the Km for L-arginine and Kact for CaM. This is based on Hayashi Y. et al. J Biol Chem. (1999) 274(29):20597...
2005-01-01 | MODEL4780784080 | BioModels
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