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ProteomicsIdentification and drug-induced reversion of molecular signatures of Alzheimer´s disease onset and progression in AppNL-G-F, AppNL-F and 3xTg-AD mouse models
Alzheimer´s disease (AD) is the most common form of dementia. Over fifty years of intense research have revealed many key elements of the biology of this neurodegenerative disorder. However, our understanding of the molecular bases of the disease is still incomplete, and the available medical treatm...
ORGANISM(S): Mus musculus (Mouse) 
2021-10-12 | PXD024538 | Pride
Proteomics Data-driven drug discovery Alzheimer’s disease Transcriptomics In vivo models. 
UnknownDifferential Distribution of the wlaN and cgtB Genes, Associated with Guillain-Barre Syndrome, in Campylobacter jejuni Isolates from Humans, Broiler Chickens, and Wild Birds.
Not available
S-EPMC7142995 | biostudies-literature
UnknownIdentification and drug-induced reversion of molecular signatures of Alzheimer's disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models.
Not available
S-EPMC8547095 | biostudies-literature
UnknownImpact of the Schottky Barrier and Contact-Induced Strain Variations inside the Channel on the Electrical Behavior of Monolayer MoS<sub>2</sub> Transistors.
Not available
S-EPMC12697886 | biostudies-literature
GenomicsGenome-wide map of GATA6 DNA binding in human CRC cells
We describe the genome-wide DNA-binding of GATA6 in a human CRC cell line (LS174T). GATA6 is found to bind the promoter of genes involved in the maintenance of intestinal stem cells, including genes of the Wnt and TGFbeta/BMP pathways. With this we describe a novel GATA6-dependent mechanism of stem ...
ORGANISM(S): Homo sapiens 
2014-05-20 | E-GEOD-49320 | biostudies-arrayexpress
UnknownInfluence of the Carrier Gas Flow in the CVD Synthesis of 2-Dimensional MoS<sub>2</sub> Based on the Spin-Coating of Liquid Molybdenum Precursors.
Not available
S-EPMC11547744 | biostudies-literature
TranscriptomicsCRC micrometastasis generated by AKP MTOs resolved by single cell RNAseq
Longitudinal single cell RNA-expression analysis of tumor cells along metastatic relapse. AKP mouse tumor organoids (MTOs) were implanted in the caecum and left to metastasize into the liver. Livers were collected at different timepoints post-injection and GFP+ CD45- cells were sorted in 96-well sma...
ORGANISM(S): Mus musculus 
2022-11-18 | E-MTAB-11981 | biostudies-arrayexpress
TranscriptomicsscRNAseq of mouse colorectal organoids in FOLFIRI treatment
The aim of the experiment is to elucidate changes in tumor heterogeneity upon chemotherapy treatment. The experiment includes non-treated samples, samples right after chemotherapy treatment (FOLFIRI) and organoids recovered from FOLFIRI. It was conducted in two different genetic backgrounds, AKP (Ap...
ORGANISM(S): Mus musculus 
2022-05-13 | E-MTAB-11145 | biostudies-arrayexpress
UnknownH4K20me3-Mediated Repression of Inflammatory Genes Is a Characteristic and Targetable Vulnerability of Persister Cancer Cells.
Not available
S-EPMC7617193 | biostudies-literature
UnknownTousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors.
Not available
S-EPMC6082654 | biostudies-literature
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