Sort   by:  
 Page size 
TranscriptomicsStudy of human macrophage reprogramming toward a pro-resolving profile by efferocytosis
Inflammation is a physiopathological process triggered by infection or tissue damage. Immune system initiates coordinated sequential steps in response to these danger signals. Once the threat has been contained inflammation has to be subsequently shut down. Inflammation resolution is initiated by the...
ORGANISM(S): Homo sapiens 
2021-12-01 | E-MTAB-8885 | biostudies-arrayexpress
TranscriptomicsmiR-16 Interactome in Uveal Melanoma
Chromosome 3p monosomy is associated with a poor clinical outcome of patients with uveal melanoma. Since a copy of the tumor suppressor miR-16 gene is lost for these patients, we postulated that a 3p loss may reduce the miR-16 amount and activity, promoting RNA derepression and tumor burden (loss of...
ORGANISM(S): Homo sapiens 
2022-10-04 | E-MTAB-10940 | biostudies-arrayexpress
GenomicsGain-of-function CRISPR screens identify tumor driver genes conferring melanoma cell plasticity and therapy-resistance
Most genetic events that drive melanoma development and resistance to targeted therapy have been uncovered. In contrast, and despite their increasingly recognized contribution, little is known about the non-genetic mechanisms that drive these processes. Here, we performed in vivo gain-of-function CR...
ORGANISM(S): Homo sapiens 
2021-02-03 | E-MTAB-8595 | biostudies-arrayexpress
TranscriptomicsIntegration of next-generation sequencing and proteomics data: application to the discovery of new coding events in the human spermatozoa
Proteomics and transcriptomics data were integrated in order to identify hard-to-reach uncharacterized proteins which are known to be particularly numerous in human spermatozoa. MS-identifications were launched both against UniprotKB and translated predicted ORF databases generated from four differe...
ORGANISM(S): Homo sapiens 
2025-12-30 | E-MTAB-11518 | biostudies-arrayexpress
TranscriptomicsTGFβ-induced lncRNA LINC00313 activates Wnt signalling and promotes cholangiocarcinoma progression
Cholangiocarcinoma (CCA) is a devastating liver cancer characterized by high aggressiveness and resistance to therapy, which results to poor prognosis. Signals imposed by oncogenic pathways, such as transforming growth factor β (TGFβ) frequently contribute to CCA development. In this study, we explo...
ORGANISM(S): Homo sapiens 
2024-02-05 | E-MTAB-12879 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Mycobacterium tuberculosis H37Rv treated with alpibectir or a combination of alpibectir and ethionamide against untreated controls
Alpibectir potentiates the activity of ethionamide and prothionamide, which are second-line antibiotics used for tuberculosis treatment. Both are prodrugs whose antibacterial activity depends on bioactivation by oxidases, including the Baeyer-Villiger monooxygenase MymA. Alpibectir binds the transcr...
ORGANISM(S): Mycobacterium tuberculosis 
2025-12-10 | E-MTAB-16253 | biostudies-arrayexpress
UnknownCirculating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders.
Not available
S-EPMC11587932 | biostudies-literature
UnknownCirculating myeloid-derived MMP8 in stress susceptibility and depression.
Not available
S-EPMC10901735 | biostudies-literature
UnknownTGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma
Not available
S-SCDT-10_1038-S44319-024-00075-Z | biostudies-other
TranscriptomicsGlobal gene expression analysis reveals importance of thermal effect in cellular response to millimeter wave exposure
To evaluate the effect of millimeter waves (MMW) exposure on the gene expression, we have employed whole genome microarray expression profiling. Neonatal primary Keratinocyte cells pooled from 3 healthy donors were exposed ex vivo, 3 hours at 20 mW/cm². At this condition, corresponding to the maxim...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-57135 | biostudies-arrayexpress
Sort   by:  
 Page size