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Human Perrault syndrome (PRLTS) is defined by autosomal recessive inheritance with primary ovarian insufficiency and early hearing loss. Most PRLTS disease proteins modulate mitochondrial transcription or translation. Among the genetic causes are ClpP mutations, which trigger also complete azoosperm...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD033388 | Pride
Mitochondrial acquisition was a pivotal event in eukaryotic evolution, requiring core proteins adapt to function both within the mitochondria and in the host cell. Here, we systematically profile the localization of protein isoforms generated by alternative start codon selection. We identify hundred...
ORGANISM(S): Homo sapiens (Human) 
2025-10-28 | PXD062112 | Pride
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