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MetabolomicsClinical Application Value of Ceramide and Sphingomyelin as Biomarkers for the Diagnosis of Drug-Induced Liver Injury

Background : Drug-induced liver injury (DILI) is a serious health concern that presents challenges in early detection and accurate diagnosis, thereby complicating the treatment of this liver disease. Therefore, it is crucial to explore specific biomarkers to improve the accuracy of diagnosing DIL...

2025-07-23 | MTBLS12765 | MetaboLights
TranscriptomicsGene expression profiling in acute murine autoimmune hepatitis
The etiology of autoimmune hepatitis is poorly understood but likely involves Th1 cells producing IFN-γ. BALB/c background TGF-β1-/- mice rapidly develop fulminant Th1-mediated autoimmune hepatitis. Our aims are to profile liver gene expression in TGF-β1-/- mice, to identify gene expression pathways...
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-9892 | biostudies-arrayexpress
ProteomicsBottom-up Proteomics of Saliva in Autoimmune Hepatitis and Primary Biliary Cholangitis
Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC) are autoimmune diseases that target the liver in which the immune system produces an inappropriate response to self-antigens resulting in inflammation, damage, and dysfunction of hepatic tissues. Despite progress in the understanding o...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039847 | Pride
Autoimmune hepatitis Saliva Primary biliary cholangitis Bottom-up proteomics Autoimmune liver diseases Lc-ms/ms 
UnknownHellenic Association for the Study of the Liver (HASL): revised clinical practice guidelines for autoimmune hepatitis.
Not available
S-EPMC11574148 | biostudies-literature
TranscriptomicsRNA sequencing of monocytes and microglia from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with disease course
The role of microglia and infiltrating monocytes in experimental autoimmune encephalomyelitis (EAE) pathogenesis has been controversial. To gain insight into their respective roles, we developed a method for differentiating between microglia and infiltrating monocytes in the CNS using CD44. We used ...
ORGANISM(S): Mus musculus 
2014-10-20 | E-GEOD-59725 | biostudies-arrayexpress
UnknownEpidemiology, comorbidities, treatments and outcomes of autoimmune liver diseases: A French nationwide study.
Not available
S-EPMC12519275 | biostudies-literature
UnknownQuo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024.
Not available
S-EPMC11783120 | biostudies-literature
ProteomicsDiagnostics of autoimmune hepatitis enabled by non-invasive clinical proteomics
Autoimmune hepatitis (AIH) can be challenging to distinguish from other chronic liver diseases such as metabolic dysfunction-associated steatotic liver disease (MASLD). We applied advanced proteomic analysis to paired liver and plasma samples from newly diagnosed AIH patients, MASLD patients, and he...
ORGANISM(S): Homo sapiens (Human) 
2025-07-17 | PXD065892 | Pride
Human Plasma Liver Aih 
UnknownAntigen-Specific Immunotherapy for Treatment of Autoimmune Liver Diseases.
Not available
S-EPMC7385233 | biostudies-literature
UnknownRole of microbiome in autoimmune liver diseases.
Not available
S-EPMC11407779 | biostudies-literature
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