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Secondary muscle atrophy due to neuronal denervation is a key determinant of poor functional recovery in immune-mediated neuropathies, even after resolution of inflammation. Activin II receptors (ActIIRs) are central mediators of muscle atrophy, and their inhibition has shown variable efficacy in pr...
ORGANISM(S): Rattus rattus (Black rat) 
2026-04-13 | PXD070456 | Pride
Transcriptomes in the Sciatic Nerves of Lewis Rats with Experimental Autoimmune Neuritis
Guillain-Barré syndrome (GBS) is characterized by acute immune-mediated peripheral neuropathy, which may result in rapidly progressive paralysis and fatal respiratory failure. As the underlying pathological mechanisms of GBS are unclear, we surveyed the transcriptome of rats with experimental autoim...
ORGANISM(S): Rattus norvegicus 
2020-01-22 | GSE133750 | GEO
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