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ProteomicsPhosphopeptide mass spectrometry analysis of LATS2 identifies a second autophosphorylation site in HEK293A cells
This dataset contains phosphopeptide LC-MS/MS data generated from human LATS2 overexpressed in HEK293A cells. The study was designed to identify LATS2 phosphorylation sites and to support phosphopeptide mapping of LATS2 autophosphorylation, with particular attention to the kinase-domain CLS site. Im...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD076693 | Pride
Homo sapiens  hek293a  lats2  hippo pathway  autophosphorylation  phosphopeptide  lc-ms/ms  kinase 
ProteomicsAnalysis of PKD1 autophosphorylation in vitro and confirmation of stoichiometric S742 phosphorylation of a recombinant PRKD1 kinase domain
Protein kinase D1 (PRKD1, also referred to as PKD1), has been proposed to undergo autophosphorylation on serine 742 and potentially also on serine 738 in the activation loop of its kinase domain. We used recombinant PKD1 kinase domain to test whether PKD1 is indeed able to undergo autophosphorylatio...
ORGANISM(S): Homo sapiens (Human) 
2019-08-19 | PXD013216 | Pride
Pkd1 Protein kinase d 
ProteomicsPhospho-mapping of MAST1 after autophosphorylation
Purified MAST1, spanning residues 116-724, underwent autophosphorylation in vitro. The resultant phosphosites on MAST1 were mapped using tandem mass spectrometry.
ORGANISM(S): Mus musculus (Mouse) 
2026-09-02 | PXD063802 | Pride
Mast1 Autophosphorylation Msms 
ProteomicsAutophosphorylation of the CK1 kinase domain regulates enzyme activity and substrate specificity
CK1 enzymes are conserved, acidophilic serine/threonine kinases with a variety of critical cellular functions; their misregulation contributes to cancer, neurodegenerative diseases, and sleep phase disorders. Here, we describe a new mechanism of CK1 regulation conserved from yeast to human – autopho...
ORGANISM(S): Schizosaccharomyces pombe 927 
2023-07-20 | PXD026766 | Pride
Casein kinase 1 Ck1 S. pombe Substrate specificity Kinase regulation 
UnknownNonconserved active site residues modulate CheY autophosphorylation kinetics and phosphodonor preference.
Not available
S-EPMC3990648 | biostudies-literature
UnknownTyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.
Not available
S-EPMC400461 | biostudies-literature
UnknownIdentification of a ubiquinone-binding site that affects autophosphorylation of the sensor kinase RegB.
Not available
S-EPMC2776112 | biostudies-literature
UnknownMechanism and functional significance of Itk autophosphorylation.
Not available
S-EPMC2753204 | biostudies-literature
UnknownTyr198 is the Essential Autophosphorylation Site for STK16 Localization and Kinase Activity.
Not available
S-EPMC6801969 | biostudies-literature
UnknownRegulation of GTPase function by autophosphorylation.
Not available
S-EPMC8986090 | biostudies-literature
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