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Serotonin regulates its own production, degradation and release in the Raphe nuclei of the brain mainly by modifying the level and activity of autoreceptors on serotonin-producing neurons, such as 5-HT1A and 5-HT1B. This autoregulation is probably the reason for the delayed response of patients with...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD055579 | Pride
Expression data from B. japonicum bll2758::aphII strain (7414) grown micro-oxically. This study includes also the expression data of a fixK2 and a fixJ mutant grown in free-living micro-oxic condition (samples GSM313721 to GSM313734 in GEO record number GSE12491) and the wild type strain grown micro...
ORGANISM(S): Bradyrhizobium japonicum 
Tubulin autoregulation mediator TTC5 regulates neuronal morphology and migration
Drawing an image of zinc homeostasis in Mycobacterium smegmatis - The critical role of Zur and SmtB autoregulation
This SuperSeries is composed of the following subset Series:; GSE11533: Autoregulation of Th1-mediated inflammation by twist1 1st part; GSE11534: Autoregulation of Th1-mediated inflammation by twist1 2nd part Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
We identified a landscape of FUS-binding RNA targets in HeLa cells. The majority of the FUS binding sites are in introns of pre-mRNAs and less are in exons and untranslated regions. Significant FUS binding in introns flanking cassette exons, long intron (>100kb) containing transcripts and noncoding...
ORGANISM(S): Homo sapiens 
Tetratricopeptide repeat domain 5 (TTC5) mediates the co-translational degradation of tubulin transcripts in response to excess soluble tubulin, a.k.a. “tubulin autoregulation”. TTC5 mutations associate with cerebral atrophy, speech and motor impairment; however, the role of TTC5 and tubulin autoreg...
ORGANISM(S): Homo sapiens 
2026-09-23 | GSE312628 | GEO
XRN2 is a conserved 5â??-->3â?? exoribonuclease that complexes with XTB-domain containing proteins. Thus, in Caenorhabditis elegans (C. elegans), the XTBD-protein PAXT-1 stabilizes XRN2 to retain its activity. XRN2 activity is also promoted by 3'(2'),5'-bisphosphate nucleotidase 1 (BPNT1) through it...
ORGANISM(S): Caenorhabditis elegans 
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