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ProteomicsInterference of RNA molecules with protein aggregation in vitro.
The analysis of RNA-protein interactomes indicates that the amount of structure in RNA molecules correlates with the capacity of binding to proteins in vitro and in vivo. To validate this observation, we used an in vitro network that mimics the composition of phase-separated RNA granules. The interf...
ORGANISM(S): Homo sapiens (Human) 
2019-09-13 | PXD011751 | Pride
B-isox Rna interactivity Rna granules 
ProteomicsStable-isotope analysis of TFA and MRFA using ESI-Orbitrap IRMS
Data analyzed within Procedure 1 in Kantnerova et al. 202X in Nature Protocols. Procedure 1 describes a direct infusion analysis using an easily accessible Orbitrap MS calibration solution FlexMix, analyzing its two compounds: a) trifluoroacetate (TFA) in the negative ESI mode, and b) the peptide MR...
ORGANISM(S): No Species 
2023-08-11 | MSV000092644 | MassIVE
ProteomicsStable-isotope analysis of TFA and MRFA using ESI-Orbitrap IRMS
Data analyzed within Procedure 1 in Kantnerova et al. 2024 in Nature Protocols (https://doi.org/10.1038/s41596-024-00981-5). Procedure 1 describes a direct infusion analysis using an easily accessible Orbitrap MS calibration solution FlexMix, analyzing its two compounds: a) trifluoroacetate (TFA) in...
ORGANISM(S): No Species 
2023-11-01 | MSV000093222 | MassIVE
UnknownBioinformatics searching of diagnostic markers and immune infiltration in polycystic ovary syndrome.
Not available
S-EPMC9471256 | biostudies-literature
GenomicsGenome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [ChIP-seq]
Intrinsically disordered regions (IDRs) in DNA-associated proteins have recently been shown to play important roles in gene regulation. To better understand these domains we developed an antibody-independent assay to map disordered proteins genome-wide by combining b-isox mediated precipitation and ...
ORGANISM(S): Homo sapiens 
2023-02-20 | GSE190960 | GEO
TranscriptomicsGenome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [RNA-Seq]
Intrinsically disordered regions (IDRs) in DNA-associated proteins have recently been shown to play important roles in gene regulation. To better understand these domains we developed an antibody-independent assay to map disordered proteins genome-wide by combining b-isox mediated precipitation and ...
ORGANISM(S): Homo sapiens 
2023-02-20 | GSE190962 | GEO
GenomicsGenome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [DisP-Seq]
Intrinsically disordered regions (IDRs) in DNA-associated proteins have recently been shown to play important roles in gene regulation. To better understand these domains we developed an antibody-independent assay to map disordered proteins genome-wide by combining b-isox mediated precipitation and ...
ORGANISM(S): Homo sapiens 
2023-02-20 | GSE190961 | GEO
GenomicsGenome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [ATAC-seq]
Intrinsically disordered regions (IDRs) in DNA-associated proteins have recently been shown to play important roles in gene regulation. To better understand these domains we developed an antibody-independent assay to map disordered proteins genome-wide by combining b-isox mediated precipitation and ...
ORGANISM(S): Homo sapiens 
2023-02-20 | GSE190959 | GEO
ProteomicsComparative analyses of vertebrate CPEB-family of proteins define two sub-families with distinct, but coordinated, functions in post-transcriptional regulation of gene expression
Background: The vertebrate CPEB-family of RNA-binding proteins promote translational repression or activation of their target mRNAs, which harbor cytoplasmic polyadenylation elements (CPEs) in their 3’ UTRs, through cytoplasmic changes in their poly(A) tail lengths. However, their regulation(s) and ...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2022-10-05 | PXD033349 | Pride
Mrna translation Deadenylation Cpeb Phosphorylation Ccr4-not complex Phase-separation Bioid 3’utr 
GenomicsGenome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [RNA-Seq]
Genome-wide profiling and identification of disordered transcription factors through chemical precipitation mapping [RNA-Seq]
PRJNA789189 | ENA
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