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ProteomicsBovine Respiratory Disease Complex
Bovine respiratory epithelial cells have different susceptibility to bovine respiratory syncytial virus infection. The cells derived from the lower respiratory tract were significantly more susceptible to the virus than those derived from the upper respiratory tract. Pre-infection with virus of lowe...
ORGANISM(S): Bos Taurus 
2020-07-28 | PXD019509 | JPOST Repository
TranscriptomicsGlobal transcriptome analysis of B. burgdorferi during adherence and invasion of human neuroglial cells
As adherence and entry of a pathogen into a host cell are two key components to an infection, identifying the molecular mechanisms responsible for cellular association will provide a better understanding of a microbe’s ability for pathogenesis. We previously established an in vitro model for B. b...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-8219 | biostudies-arrayexpress
TranscriptomicsCharacterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression Moraxella catarrhalis strain BBH18 during adherence to human phanryngeal epithelial Detroit 562 cells
During the course of infection, respiratory pathogens like Moraxella catarrhalis needs to adhere to epithelial cells of different host niches such as the nasopharynx and lungs. Consequently, efficient adhesion to epithelial cells is considered an important virulence trait of M. catarrhalis. We exam...
ORGANISM(S): Moraxella catarrhalis 
2013-06-27 | E-GEOD-47870 | biostudies-arrayexpress
TranscriptomicsThe plasmid-borne Type II Secretion System of Escherichia coli O157:H7 isolate Sakai mediates adherence to spinach. Experiment 1: screening E coli O157:H7 Sakai genes for adherence to spinach roots.
Food-borne illness arising for Shiga-toxigenic Escherichia coli is often linked to consumption of fruit and vegetables as the bacteria have the ability to interact with plants and use them as alternative or secondary hosts. Attachment of the bacteria to host tissue is one of the first steps in the ...
ORGANISM(S): Escherichia coli 
2019-11-20 | E-MTAB-5923 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli NMB0419 mutants to investigate the role of this tetratricopeptide-repeats-encoding gene in bacterial adherence to human epithelial cells
The gene NMB0419 of Neisseria meningitidis strain MC58 encodes a putative tetratricopeptide repeats (TPR) containing protein, which was implicated in respiratory epithelial invasion. We have accordingly sought a role for NMB0419 in meningococcal adherence and invasion of human epithelial cells using...
ORGANISM(S): Escherichia coli 
2010-11-27 | E-MEXP-2485 | biostudies-arrayexpress
ProteomicsDynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics
Epithelial colonisation is often a critical first step in bacterial pathogenesis, however, different bacterial species utilise several different receptors at the cell membrane interface to adhere to cells. We have previously demonstrated that interference of the human tetraspanin, CD9, can reduce ad...
ORGANISM(S): Neisseria meningitidis serogroup B Homo sapiens (Human) Staphylococcus aureus 
2025-10-28 | PXD067302 | Pride
Neisseria meningitidis Staphylococcus aureus Cde9 
ProteomicsDynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics
Epithelial colonisation is often a critical first step in bacterial pathogenesis, however, different bacterial species utilise several different receptors at the cell membrane interface to adhere to cells. We have previously demonstrated that interference of the human tetraspanin, CD9, can reduce ad...
ORGANISM(S): Homo sapiens (Human) Staphylococcus aureus subsp. aureus NCTC 8325 Neisseria meningitidis serogroup B (strain MC58) 
2025-10-28 | PXD058283 | Pride
Epithelial Cd9 Neisseria meningitidis Staphylococcus aureus Bacteria Proximity labelling Tetraspanin 
TranscriptomicsM1 serotype (strain SF370): pharyngeal cell adherence vs. association
We developed spotted oligonucleotide arrays of the S. pyogenes SF370 (an M1 serotype) genome and compared the transcriptomes of streptococci that adhere to Detroit 562 human pharyngeal cells to non-adherent (“associated”) streptococci within the same experiment. We replicated experiments independent...
ORGANISM(S): Streptococcus pyogenes 
2007-04-27 | GSE7620 | GEO
TranscriptomicsThe plasmid-borne Type II Secretion System of Escherichia coli O157:H7 isolate Sakai mediates adherence to spinach. Experiment 2: control screen.
Food-borne illness arising for Shiga-toxigenic Escherichia coli is often linked to consumption of fruit and vegetables as the bacteria have the ability to interact with plants and use them as alternative or secondary hosts. Attachment of the bacteria to host tissue is one of the first steps in the ...
ORGANISM(S): Escherichia coli 
2019-11-20 | E-MTAB-5924 | biostudies-arrayexpress
GenomicsEnteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection
PRJNA756246 | ENA
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