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Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights
Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread amongst bacterial isolates and are important genetic determinants of competitive fitness. Staphylococci produce a tremendous diversity of compounds and the corresponding gene clusters (Staphylococcal Antibiosis ...
ORGANISM(S): Bacteria Staphylococcus aureus 
2022-11-21 | PXD035193 | Pride
The effect of epithelial cell-bacterial interaction on gene transcription in the epithelial cells and bacterial cells in vitro. The transcriptional response elicited by the UCC118 sortase deletion mutant will be compared to that of the wild type UCC118.
ORGANISM(S): Homo sapiens 
This project reports the identification and characterization of saprophyticin S (SapS), a novel leaderless bacteriocin produced by Staphylococcus saprophyticus P1CEA4, a strain isolated from the porcine gastrointestinal tract. MALDI-TOF MS analysis revealed SapS variants corresponding to formylated ...
ORGANISM(S): Staphylococcus saprophyticus 
2026-06-08 | PXD068573 | Pride
A popular strategy for enhancing the antibacterial properties of probiotic bacteria is to retrofit them with the ability to overproduce heterologous bacteriocins. This is often achieved from strong, non-native promoters. How the dysregulated overproduction of heterologous bacteriocins affects the fi...
ORGANISM(S): Escherichia coli 
In present study, it was found that the co-culture of Wickerhamomyces anomalus Y-5 and L. plantarum RX-8 could enhance bacteriocin production. To analyze the interaction between W. anomalus Y-5 and L. plantarum RX-8, a quantitative proteomic approach was used to analyze and compare the proteome in L...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-12-04 | PXD038315 | Pride
Horizontal transfer of bacteriocin biosynthesis genes requires metabolic adaptation to improve compound production and cellular fitness
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