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MetabolomicsHorizontal Transfer of Bacteriocin Biosynthesis Genes Requires Metabolic Adaptation To Improve Compound Production and Cellular Fitness

Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread among bacterial isolates and are important genetic determinants of competitive fitness within a given habitat. Staphylococci produce a tremendous diversity of compounds, and the corresponding BGCs are frequen...

2022-11-09 | MTBLS5196 | MetaboLights
TranscriptomicsPeptide alarmone signalling triggers an auto-active bacteriocin necessary for genetic competence
The induction of genetic competence is a strategy used by bacteria to increase their genetic repertoire under stressful environmental conditions. Recently, Streptococcus pneumoniae has been shown to co-ordinate the uptake of transforming DNA with fratricide via increased expression of the peptide ph...
ORGANISM(S): Streptococcus mutans UA159 
2010-05-29 | E-GEOD-22019 | biostudies-arrayexpress
ProteomicsBacteriocin producing Enterococcus faecium
Proteomic Characterization of Bacteriocin-Producing Enterococcus faecium Strains from foodstuffs
ORGANISM(S): Enterococcus faecium Bacteria 
2023-03-11 | PXD037241 | Pride
Enterococcus Bacteriocins 
ProteomicsBacteriocin LC-MSMS
This is the first report of a bacteriocin being produced by lactobacillus acidophilus ATCC 4356. For protein identification, the ~8-kDa peptide band was removed from the acrylamide gel and digested in-gel by trypsin, and the resulting peptide fragments were extracted and analyzed by LC-MS/MS analysi...
ORGANISM(S): Lactobacillus acidophilus 
2020-03-24 | PXD011556 | Pride
Lactobacillus acidophilus atcc 4356 Bacteriocin 
TranscriptomicsTranscriptional changes associated to resistance to the cell wall active bacteriocin Lcn972
Lcn972 is a non-modified bacteriocin that targets exclusively Lactococcus sp. Addition of Lcn972 inhibits cell wall biosynthesis at the septum by binding to the cell wall precursor lipid II. Resistance to Lcn972 develops upon selection with subinhibitory concentrations. The transcriptome of the high...
ORGANISM(S): Lactococcus lactis subsp. lactis 
2012-12-06 | E-GEOD-38349 | biostudies-arrayexpress
ProteomicsImpact of bacteriocin production on cellular metabolism of Staphylococcus aureus
Biosynthetic gene clusters (BGCs) encoding the production of bacteriocins are widespread amongst bacterial isolates and are important genetic determinants of competitive fitness. Staphylococci produce a tremendous diversity of compounds and the corresponding gene clusters (Staphylococcal Antibiosis ...
ORGANISM(S): Bacteria Staphylococcus aureus 
2022-11-21 | PXD035193 | Pride
Bacteriocin production Citrate synthase Tca Staphylococcus aureus 
ProteomicsProteomic validation of saprophyticin S (SapS), a novel leaderless bacteriocin from Staphylococcus saprophyticus P1CEA4
This project reports the identification and characterization of saprophyticin S (SapS), a novel leaderless bacteriocin produced by Staphylococcus saprophyticus P1CEA4, a strain isolated from the porcine gastrointestinal tract. MALDI-TOF MS analysis revealed SapS variants corresponding to formylated ...
ORGANISM(S): Staphylococcus saprophyticus 
2026-06-08 | PXD068573 | Pride
Saprophyticin s  bacteriocin  leaderless bacteriocin  saposin-like fold  antimicrobial peptide  staphylococcus saprophyticus  lc-ms/ms  maldi-tof  antimicrobial resistance 
ProteomicsIdentification and quantification of mediterrocin, a bacteriocin produced by Mediterraneibacter gnavus
Mediterraneibacter gnavus, a core member of the human gut microbiota, secretes mediterrocin, a broad-spectrum bacteriocin. Identification and quantification of mediterrocin produced by Mediterraneibacter [Ruminococcus] gnavus strains RJX1121, RJX1123, and ATCC29149 using intact protein analysis.
ORGANISM(S): [ruminococcus] Gnavus (ncbitaxon:33038) 
2024-08-27 | MSV000095709 | MassIVE
ProteomicsProteome of Listeria monocytogenes FBUNT biofilm cells and response to bacteriocin AL705
L. monocytogenes FBUNT is able to form biofilm after six days at 10 ºC. Proteome under planktonic growth, lactocin AL705-treated and untreated biofilms was analyzed. Compared to planktonic cells, protein abundance shifts associated with ribosomes function and biogenesis, cell membrane functionality,...
ORGANISM(S): Listeria monocytogenes serotype 4b str. 02-6679 
2021-09-09 | PXD022168 | Pride
L. monocytogenes Bacteriocin Proteomic Biofilm 
Genomicspotential bacteriocin producing gut isolates
Bacteriocin-producing gut isolates, recovered from the faecal microbiome of Irish athletes
PRJEB48530 | ENA
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