Bahcc1 - OmicsDI

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1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 5Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA 8Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA (1)
Department of Immunology and Regenerative Biology and Department of Molecular Neuroscience, Weizmann Institute of Science, Rehovot 76100, Israel (1)
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Identification of BAHCC1 protein interactors

Trimethylation of histone H3 lysine 27 (H3K27me3) regulates gene repression, cell-fate determination and differentiation. We report that a conserved Bromo-Adjacent Homology (BAH) module of BAHCC1 (BAHCC1BAH) ‘recognizes’ H3K27me3 specifically and enforces silencing of H3K27me3-demarcated genes in ma...

ORGANISM(S): Homo sapiens (Human)

2020-11-05 | PXD021679 | Pride

Ap-ms Bahcc1

BAHCC1 promotes gene expression in neuronal cells by antagonizing SIN3A-HDAC1

Chromatin modifications play a key role in regulating gene expression during development and adult physiology. Histone acetylation, particularly H3K27ac, is associated with increased activity of gene regulatory elements such as enhancers and promoters. However, the regulation of the machinery that w...

ORGANISM(S): Homo sapiens (Human)

2025-06-12 | PXD058811 | Pride

Neurons Acetylation Sin3a Hdac Bahcc1

Transcriptional dysregulation of BAHCC1 in melanoma [CUT&TAG_BAHCC1]

PRJNA1034547 | ENA

Transcriptional dysregulation of BAHCC1 in melanoma [CUT&Tag]

PRJNA846108 | ENA

Transcriptional dysregulation of BAHCC1 in melanoma [RNA-seq]

PRJNA832708 | ENA

BAHCC1 promotes gene expression in neuronal cells by antagonizing SIN3A-HDAC1.

Not available

S-EPMC12276004 | biostudies-literature