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TranscriptomicsGenome-wide Analyses of Diffuse Intrinsic Pontine Gliomas
Purpose: More than 90% of children with diffuse intrinsic pontine glioma (DIPG) die within 2 years of diagnosis. There is a dire need to identify therapeutic targets, however lack of patient material for research has limited progress. We evaluated a large cohort of diffuse intrinsic pontine gliomas ...
ORGANISM(S): Homo sapiens 
2011-09-20 | E-GEOD-26576 | biostudies-arrayexpress
UnknownThe HLA-B 3906 allele imparts a high risk of diabetes only on specific HLA-DR/DQ haplotypes.
Not available
S-EPMC3110277 | biostudies-literature
UnknownInsulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes.
Not available
S-EPMC9399855 | biostudies-literature
ProteomicsShotgun proteomics of heterologously generated proteins and proteins in gel bands
We performed shotgun proteomics on the heterolously generated proteins and proteins in gel bands.
ORGANISM(S): Escherichia coli 
2026-07-29 | PXD070885 | Pride
Lc-ms/ms 
ProteomicsA Parts List for Fungal Cellulosomes Revealed by Comparative Genomics
Characterization of proteins critical to fungal cellulosome assembly for Anaeromyces robustus, Neocallimastix californiae and Piromyces finnis (cellulosomes are multi-protein complexes that tether plant biomass degrading enzymes together). These findings suggest that the fungal cellulosome is an ind...
ORGANISM(S): Anaeromyces Piromyces sp. Neocallimastix sp. G-1 
2018-10-19 | PXD006325 | Pride
Anaerobic Fungi Cellulosomes 
TranscriptomicsIntegrated molecular genetic profiling of pediatric-high grade gliomas reveals key differences with adult disease
Purpose: To define copy number alterations and gene expression signatures underlying pediatric high-grade glioma (HGG). Patients and Methods: We conducted a high-resolution analysis of genomic imbalances in 78 de novo pediatric HGG, including 7 diffuse intrinsic pontine gliomas, and 10 HGG cases ar...
ORGANISM(S): Homo sapiens 
2010-06-15 | E-GEOD-19578 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of commercial wine strains
Microarray karyotyping (aCGH) of three independent isolates each of four different commerical wine yeast strains was performed. Duplicate arrays (labeled "A" and "B") were performed for each isolate.
ORGANISM(S): Saccharomyces cerevisiae 
2005-07-06 | E-SMDB-3267 | biostudies-arrayexpress
ProteomicsStrategic Reduction of Hybrid Insulin Peptide Formation Significantly Delays Diabetes Onset in NOD Mice
Hybrid insulin peptides (HIPs) form in pancreatic beta cells through the covalent cross-linking of proinsulin peptides with various beta cell peptides, creating unique amino acid sequences not encoded in the genome. HIPs have been confidently identified in both human and mouse islets by mass spectro...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-12-22 | PXD063329 | Pride
Nod Hybrid insulin peptides Insulin Type 1 diabetes 
ProteomicsHDAC inhibition improves cardiopulmonary and mitochondrial function in a feline model with features of Heart Failure with Preserved Ejection Fraction
Heart Failure with preserved Ejection Fraction (HFpEF) is a major global health problem but there are no effective therapies. The aim of this study was to assess the effects of histone deacetylase (HDAC) inhibition on cardiopulmonary structure, function, and metabolism in a large mammalian (feline) ...
ORGANISM(S): Felis catus (Cat) (Felis silvestris catus) 
2021-09-08 | PXD013663 | Pride
Myofibril relaxation Hypertrophy Cat Hdac Heart failure Acetylation proteomics Pulmonary hypertension Lung compliance 
TranscriptomicsCommercialWineYeastStrainsCGH
Microarray karyotyping (aCGH) of three independent isolates each of four different commerical wine yeast strains was performed. Duplicate arrays (labeled "A" and "B") were performed for each isolate. An all pairs experiment design type is where all labeled extracts are compared to every other label...
ORGANISM(S): Saccharomyces cerevisiae 
2005-07-16 | E-GEOD-2949 | biostudies-arrayexpress
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