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ProteomicsCronobacter sakazakii infection implicates multifaceted neuro-immune regulatory pathways of Caenorhabditis elegans
Background: The nervous and immune systems are inextricably interlinked. Protein therapy strategies are the most advanced methods for treating neurodegenerative diseases. Albeit the technologies and facilities have developed in modern medicine, still there are no proper treatments to pathogen specif...
ORGANISM(S): Caenorhabditis elegans 
2023-10-13 | PXD041315 | Pride
Caenorhabditis elegans  cronobacter sakazakii  mtor pathway  protein aggregation  lc-ms/ms  western blotting  apoptosis. 
Proteomicsp38-MAPK recruits the proteolysis pathways in Caenorhabditis elegans during bacterial infection
TiO2 column chromatography, MALDI-ToF-MS, SUMOylation, Coimmunoprecipitation and LC-MS/MS
ORGANISM(S): Caenorhabditis elegans 
2022-04-06 | PXD019172 | Pride
Sumoylation Tio2 column chromatography Maldi-tof-ms Coimmunoprecipitation and lc-ms/ms 
ProteomicsProteomic analysis of Caenorhabditis elegans wound model reveals novel molecular players involved in repair
Now a days, wound healing is becoming a global threat that impact economy of the country severely. Though the steps involved in wound healing are well characterised, direct therapeutics for the accelerated wound healing is comparatively less. This is solely because of the incomplete mechanism of hea...
ORGANISM(S): Caenorhabditis elegans 
2021-04-16 | PXD024744 | Pride
C.elegans Whole body Injury Lcms/ms 
ProteomicsGlobal proteomic analysis of changes in the Caenorhabditis elegans proteome during Klebsiella pneumoniae infection
In this study, the changes in the global proteomics of C. elegans were analyzed by proteomics approach. The nematodes were exposed to K. pneumoniae for different time-points (12, 24 and 36 h) and the changes in the regulation were analyzed by employing mass spectrometry.
ORGANISM(S): Caenorhabditis elegans 
2017-09-06 | PXD007151 | Pride
Caenorhabditis elegans Ms Klebsiella pneumoniae Proteomics 
ProteomicsExploring Diabesity Pathophysiology Through Proteomic Analysis Using Caenorhabditis elegans
Diabesity, characterized by obesity-driven Type 2 diabetes mellitus (T2DM), arises from intricate genetic and environmental interplays that induce various metabolic disorders. The systemic lipid and glucose homeostasis is controlled by an intricate cross-talk of internal glucose/insulin and fatty ac...
ORGANISM(S): Caenorhabditis elegans 
2024-10-24 | PXD057033 | Pride
And immunofluorescence C. elegans Triglyceride Lipids Diabesity Proteomics Atgl-1 
ProteomicsProteomic analysis of Caenorhabditis elegans wound model reveals novel molecular players involved in repair
Now a days, wound healing is becoming a global threat that impact economy of the country severely. Though the steps involved in wound healing are well characterised, direct therapeutics for the accelerated wound healing is comparatively less. This is solely because of the incomplete mechanism of hea...
ORGANISM(S): Caenorhabditis elegans 
2021-04-16 | PXD024629 | Pride
C. elegans 2-d ge Whole body Injury 
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