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TranscriptomicsComparative transcriptome analysis between original and evolved recombinant lactose-consuming S. cerevisiae strains
The engineering of Saccharomyces cerevisiae strains for lactose utilization has been attempted with the intent of developing high productivity processes for alcoholic fermentation of cheese whey. A recombinant S. cerevisiae flocculent strain that efficiently ferments lactose to ethanol was previousl...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-31 | E-GEOD-12433 | biostudies-arrayexpress
TranscriptomicsGenomics of colony founding in fire ants - pleo1
Fire ant queens were collected immediately after a nuptial mating flight and split into two groups: paired queens (pleometrosis) and individual queens(haplometrosis). All the queens were provided with a nesting chamber consisting of a glass tube half-filled with water, which was covered by a cotton ...
ORGANISM(S): Solenopsis invicta 
2013-08-21 | E-MEXP-3886 | biostudies-arrayexpress
MetabolomicsUntargeted Metabolomics for Integrative Taxonomy: Metabolomics, DNA Marker-Based Sequencing, and Phenotype Bioimaging

Integrative taxonomy is a fundamental part of biodiversity and combines traditional morphology with additional methods such as DNA sequencing or biochemistry. Here, we aim to establish untargeted metabolomics for use in chemotaxonomy. We used three thallose liverwort species Riccia glauca

2026-01-30 | MTBLS4668 | MetaboLights
TranscriptomicsNAC, Tiron and Trolox impair GBM tumorigenic cell survival by mechanisms independent from antioxidant activity
The aim of this study is to determine if, using antioxidant drugs, it is possible to interfere with the proliferative capabilities of the human glioblastoma (GBM) tumor-initiating cells (TICs). To establish which cellular processes are activated in GBM TICs by the antioxidants NAC, Tiron and Trolox,...
ORGANISM(S): Homo sapiens 
2014-03-04 | E-GEOD-44099 | biostudies-arrayexpress
TranscriptomicsThe glucosinolate metabolite 1-methoxy-3-indolylmethyl alcohol induces a gene expression profile in mouse liver similar to the expression signature caused by known genotoxic hepatocarcinogens
Breakdown products of some glucosinolates M-bM-^@M-^S defense chemicals of Brassicales M-bM-^@M-^S induce detoxifying enzymes and demonstrate preventive activities against chemically induced tumorigenesis in animal models. However, other breakdown products are genotoxic. 1-Methoxy-3-indolylmethyl al...
ORGANISM(S): Mus musculus 
2015-02-18 | E-GEOD-61494 | biostudies-arrayexpress
MetabolomicsMetabolic signatures of Arabidopsis thaliana abiotic stress responses elucidate patterns in stress priming, acclimation, and recovery

Temperature, water and light are 3 abiotic stress factors that have major influences on plant growth, development and reproduction. Plants can be primed by a prior mild stress to enhance their resistance to future stress. We used an untargeted metabolomics approach to examine Arabidopsis thal...

2022-05-30 | MTBLS3672 | MetaboLights
TranscriptomicsChIP on chip data for AbrC3 binding sites in S. coelicolor M145
ChIP on chip assay of AbrC3 to determine its binding sites in S. coelicolor M145 genome using purified anti-AbrC3 polyclonal antibodies. Samples from nutrient broth (NB) cultures were collected at 36, 48 and 60 hours, cross-linked, and finally hybridized to DNA 104K microarrays designed by Universit...
ORGANISM(S): Streptomyces coelicolor A3(2) 
2014-01-04 | E-MTAB-1451 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae TPP 2-oxo acid decarboxylases
The irreversible decarboxylation step, which commits 2-oxo acids to the Ehrlich pathway, was initially attributed to pyruvate decarboxylase. However, the yeast genome was shown to harbour no fewer than 5 genes that show sequence similarity with thiamine-diphosphate dependent decarboxylase genes. Thr...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9590 | biostudies-arrayexpress
TranscriptomicsMicroRNA signatures predict Estrogen receptor, Progesterone receptor and HER2/neu receptor status in Breast Cancer
Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the estrogen, progesterone and HER2/neu receptors which characterise clinically distinct breast tumors have been shown to change during disease progression and in response to system...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15885 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
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