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TranscriptomicsGene expression profiling associated with the progression to poorly differentiated thyroid carcinomas
Poorly differentiated thyroid carcinomas (PDTC) represent a heterogeneous, aggressive entity, presenting features that suggest a progression from well-differentiated carcinomas. To elucidate the mechanisms underlying such progression and identify novel therapeutical targets, we assessed the genome-w...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-53157 | biostudies-arrayexpress
ProteomicsSuper-enhancer-driven CACNA2D2 is an EWSR1::WT1 signature gene encoding a diagnostic marker for desmoplastic small round cell tumor (DSRCT)
Desmoplastic small round cell tumor (DSRCT) is a highly aggressive cancer predominantly occurring in young male adolescents. It mainly arises at sites lined by mesothelium, such as the abdominal cavity, and is driven by the pathognomonic EWSR1::WT1 fusion oncoprotein. The dismal survival rates (5–20...
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD053786 | Pride
Super-enhancer Dsrct Proteomics Scrna-seq Cacna2d2 Ewsr1::wt1 Ihc Biomarker 
TranscriptomicsAnalysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant
We expressed either a wt or a phosphomutant version of ZFP36L1 in IMR90 ER:RAS cells. 7 days upon RAS induction (when the cells reach a fully senescent phenotype) we collected the RNA. ZFP36L1 is a RNA binding protein that binds to AU-rich elements in the 3’UTR of mRNAs and triggers their degradat...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-61130 | biostudies-arrayexpress
UnknownGene expression profiling associated with the progression to poorly differentiated thyroid carcinomas.
Not available
S-EPMC2778548 | biostudies-literature
UnknownA Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1.
Not available
S-EPMC6606372 | biostudies-literature
UnknownMulti-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Not available
S-EPMC10761971 | biostudies-literature
UnknownSomatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas.
Not available
S-EPMC12170903 | biostudies-literature
UnknownCoupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
Not available
S-EPMC5733499 | biostudies-literature
UnknownSynovial Sarcoma Chromatin Dynamics Reveal a Continuum in SS18:SSX Reprograming.
Not available
S-EPMC11118320 | biostudies-literature
UnknownA Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18-SSX Induces Canonical BAF Destruction.
Not available
S-EPMC8567602 | biostudies-literature
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