Sort   by:  
 Page size 
TranscriptomicsExpression data from human cord blood CD161++/CD161+/CD161- CD8+ T cell subsets
We used microarray to compare gene expression between CD161++/CD161+/CD161-CD8+ T cells from human cord blood. Lymphocytes from freshly obtained human cord blood samples were isolated by Ficoll density centrifugation. CD8+ T cells were purified by negative selection using magnetic beads and subseque...
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-33424 | biostudies-arrayexpress
TranscriptomicsExpression data from healthy human CD161++CD8aa and CD161++CD8ab T cells
We used microarrays to compare gene expression between healthy human CD161++CD8aa and CD161++CD8ab T cells. We sorted freshly obtained peripheral blood mononucleocytes from healthy controls by first using magnetic beads to negatively select for CD8a+ T cells, fluorescently labelling isolated cells w...
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-33374 | biostudies-arrayexpress
MetabolomicsToxicometabolomics of the new psychoactive substances α-PBP and α-PEP studied in HepaRG cell incubates by means of untargeted metabolomics revealed unexpected amino acid adducts
Toxicometabolomics, essentially applying metabolomics to toxicology of endogenous compounds such as drugs of abuse or new psychoactive substances (NPS), can be investigated by using different in vitro models and dedicated metabolomics techniques to enhance the number of relevant findings. The presen...
2023-10-10 | MTBLS1481 | MetaboLights
TranscriptomicsHuman MAIT and CD8++ cell development
This SuperSeries is composed of the following subset Series: GSE33374: Expression data from healthy human CD161++CD8aa and CD161++CD8ab T cells GSE33424: Expression data from human cord blood CD161++/CD161+/CD161- CD8+ T cell subsets Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-01-25 | E-GEOD-33425 | biostudies-arrayexpress
TranscriptomicsGene expression changes during retinal development and rod specification.
Photoreceptor disorders are collectively known as retinal degeneration (RD), and include retinitis pigmentosa (RP), cone-rod dystrophy and age related macular degeneration (AMD). These disorders are largely genetic in origin; individual mutations in any one of >200 genes cause RD, making mutation sp...
ORGANISM(S): Mus musculus 
2015-01-20 | E-GEOD-59201 | biostudies-arrayexpress
TranscriptomicsImmune cells direct epithelial maturation during early human lung development
The adult human lung harbours a significant proportion of immune cells, which are known to play a crucial role in both normal lung homeostasis and pathogenesis. In this work, we collected CD45-enriched human lung cells from 6 to 22 week post conception (pcw) and built a single-cell transcriptome and...
ORGANISM(S): Homo sapiens 
2022-12-09 | E-MTAB-11528 | biostudies-arrayexpress
TranscriptomicsIdentification of cell-intrinsic effects of clonal hematopoiesis in heart failure
Clonal hematopoiesis of indeterminate potential (CHIP) is caused by somatic mutations in hematopoietic stem cells and is associated with worse prognosis in heart failure patients. Patients harboring CHIP mutations show enhanced inflammation. However, whether these signatures are derived from the rel...
ORGANISM(S): Homo sapiens 
2023-06-15 | E-MTAB-13016 | biostudies-arrayexpress
TranscriptomicsRNA-Seq study of skin and blood samples from prospectively-recruited, deeply-phenotyped discovery and refinement psoriasis cohorts, during targeted treatment with adalimumab or ustekinumab
The Psoriasis Stratification to Optimise Relevant Therapy (PSORT) consortium, prospectively recruited deeply-phenotyped discovery and refinement psoriasis patient cohorts, during the early phase of treatment with two distinct biologics, adalimumab (TNF inhibitor) and ustekinumab (IL-12/23 inhibitor)...
ORGANISM(S): Homo sapiens 
2025-11-19 | E-MTAB-14509 | biostudies-arrayexpress
TranscriptomicsIntracellular expression pattern of recombinant Mtb strain TB294 overexpressing sigma factor A
We previously showed that increased expression of the principal sigma factor, SigA, mediates the capacity of Mycobacterium tuberculosis 210 strains to grow more rapidly in human monocytes, compared to other strains. To identify SigA-regulated genes that favor intracellular mycobacterial growth, we u...
ORGANISM(S): Mycobacterium tuberculosis 
2010-10-08 | E-GEOD-13780 | biostudies-arrayexpress
ProteomicsO-GlcNAc Containing Proteins in Normal and Idiopathic Pulmonary Fibrosis Human Fibroblasts
Isolated normal and IPF fibroblasts were homogenized in cold MilliQ water using a bullet blender. Samples were centrifuged and inhibitors were added: HALT (Thermo Fisher Scientific), Z-Pugnac (Tocris), Thiamet G (Cayman Chemicals), and benzonase (E1014, Millipore, Sigma). O-GlcNAc enzymatic labeling...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-21 | MSV000093453 | MassIVE
Sort   by:  
 Page size