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Much of posttranscriptional mRNA regulation occurs through cis-acting sequences in mRNA 3´ untranslated regions (UTRs), which interact with specific proteins and ribonucleoprotein complexes that modulate translation, mRNA stability and subcellular localization. Studies in Caenorhabditis elegans hav...
ORGANISM(S): Caenorhabditis elegans 
Protein secretion is key for bacterial growth, survival and adaptation. In the Gram-positive bacterium Bacillus subtilis, the twin-arginine (Tat) pathway serves in the exclusive secretion of proteins with bound cofactors. The Bacillus Tat pathway stands out for its minimalist nature with two indepen...
ORGANISM(S): Bacillus subtilis subsp. subtilis 
2022-08-11 | PXD012842 | Pride
Recently, endolysosomal cation channels have emerged as an attractive anti-cancer target: namely the mucolipin subfamily of transient potential receptors (TRPMLs), which comprises three isoforms – TRPML1 (MCOLN1), TRPML2 (MCOLN2), and TRPML3 (MCOLN3). TRPML1, the most intensively researched member o...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-20 | PXD046212 | Pride
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