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ProteomicsInitial effects of BBN treatment on mouse bladder
Characterizing the initial stages of oncogenic transformation in bladder cancer. Littermate male mice were transferred in single-use plastic cages in order to be treated with the BBN carcinogen. The treatment dose used in this work was 0.05% BBN delivered in drinking water for up to 12 days. Bladde...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-12 | PXD054745 | Pride
Bbn Mouse Bladder 
UnknownNickel-Catalyzed Enantioselective Conjunctive Cross-Coupling of 9-BBN Borates.
Not available
S-EPMC5699474 | biostudies-literature
UnknownThe dynamics of the inflammatory response during BBN-induced bladder carcinogenesis in mice.
Not available
S-EPMC6883615 | biostudies-literature
GenomicsMulti-stage expression in BBN mouse model reveals progression-associated molecular changes in basal/squamous and sarcomatoid bladder carcinogenesis
Multi-stage expression in BBN mouse model reveals progression-associated molecular changes in basal/squamous and sarcomatoid bladder carcinogenesis
PRJNA808403 | ENA
GenomicsWhole transcriptome sequencing for upper tract urothelial carcinoma (UTUC) of BALB/c female mice treated with N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)
Whole transcriptome sequencing for upper tract urothelial carcinoma (UTUC) of BALB/c female mice treated with N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)
PRJNA1144834 | ENA
MetabolomicsGut microbiota carcinogen metabolism causes distal tissue tumours

Exposure to environmental pollutants and human microbiome composition are important predisposition factors for tumour development. Similar to drug molecules, pollutants are typically metabolised in the body, which can change their carcinogenic potential and impact tissue distribution through alte...

2024-06-05 | MTBLS3581 | MetaboLights
UnknownA novel, synthesized, amphiphilic ethylene glycol squalene derivative suppresses BBN-induced bladder carcinogenesis.
Not available
S-EPMC12370948 | biostudies-literature
TranscriptomicsGene expression study for effectiveness of nicotinamide using chemically-induced mouse bladder cancer model
The objective of this study was to evaluate the efficacy of nicotinamide in a N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN)-induced urinary bladder cancer model in mice, and to identify through gene expression profiling the molecular signatures of cancer prevention by nicotinamide. We used 20 mice fo...
ORGANISM(S): Mus musculus 
2011-12-12 | E-GEOD-21636 | biostudies-arrayexpress
TranscriptomicsMulti-stage expression in BBN mouse model reveals progression-associated molecular changes in basal/squamous and sarcomatoid bladder carcinogenesis
RNA-seq data of microdissected lesions occurring in C57BL/6 male mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) and normal control urothelium from untreated mice.
ORGANISM(S): Mus musculus 
2023-01-18 | GSE197016 | GEO
TranscriptomicsExpression data from the bladders of carcinogen-treated mice with genetic Hh pathway manipulation
Attenuation of Hedgehog (Hh) pathway activity leads to accelerated tumor progression in a mouse model of N-butyl-N-4-hydroxybutyl nitrosamine (BBN) – induced bladder carcinoma. In order to identify genes regulated by the Hh pathway that might be involved in bladder cancer progression, we performed t...
ORGANISM(S): Mus musculus 
2014-08-27 | E-GEOD-60654 | biostudies-arrayexpress
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