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TranscriptomicsTranscription profiling of mouse skeletal muscle overexpressing PPARalpha
This experiment was conducted to identify target genes of the peroxisome proliferator-activated receptor alpha (PPARa) in skeletal muscle of transgenic mice that overexpressed PPARa. The following abstract from the published manuscript describes the major findings of this work. A potential link betw...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-5777 | biostudies-arrayexpress
UnknownInterrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Not available
S-EPMC5572896 | biostudies-literature
TranscriptomicsGene Expression Analysis Of Plasmablastic Lymphoma Identifies Down Regulation Of B Cell Receptor Signaling and Additional Unique Transcriptional Programs
Plasmablastic lymphoma is a high grade B cell lymphoma with plasmablastic morphology and a terminally differentiated B cell immunophenotype, usually arising in the setting of immunodeficiency and often demonstrating Epstein Barr Virus positivity. The molecular and genetic mechanisms underlying the ...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-53117 | biostudies-arrayexpress
UnknownThe role of NF-{kappa}B-1 and NF-{kappa}B-2-mediated resistance to apoptosis in lymphomas.
Not available
S-EPMC1482593 | biostudies-literature
UnknownA time to kill: targeting apoptosis in cancer.
Not available
S-EPMC4346874 | biostudies-literature
UnknownNoninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eye.
Not available
S-EPMC4878273 | biostudies-literature
UnknownGestational exposure to metformin programs improved glucose tolerance and insulin secretion in adult male mouse offspring.
Not available
S-EPMC5893596 | biostudies-literature
TranscriptomicsReal-time quantitative PCR analysis of microRNAS in islets of mice exposed to low-protein diet during gestation
Maternal low-protein diet increases the susceptibility of offspring to type 2 diabetes. An insult to the pancreas during development can have long-term consequences on ?-cell mass and function. Because nutrients and growth factors signaling converge on mTOR, we hypothesized that mTOR plays a central...
ORGANISM(S): Mus musculus 
2014-07-11 | E-GEOD-59279 | biostudies-arrayexpress
UnknownIslet pericytes convert into profibrotic myofibroblasts in a mouse model of islet vascular fibrosis.
Not available
S-EPMC7354906 | biostudies-literature
UnknownOverexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass.
Not available
S-EPMC5521866 | biostudies-literature
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