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TranscriptomicsTranscriptional profiling of 7SK knockdown in mouse embryonic stem cells
Transcriptome profiling of mouse embryonic stem cells following antisense knockdown of the non-coding RNA 7SK.
ORGANISM(S): Mus musculus 
2013-09-09 | E-MTAB-1585 | biostudies-arrayexpress
TranscriptomicsRNA sequencing of marmoset embryonic development
Transcriptional profiling of common marmoset embryo stages spanning E5.0 to E7.0 was performed by RNA-seq.
ORGANISM(S): Callithrix jacchus 
2015-11-05 | E-MTAB-2959 | biostudies-arrayexpress
GenomicsChIP-seq analysis of Foxa2 binding sites in midbrain dopaminergic progenitors
Embryonic stem (ES) cells were differentiated in culture to midbrain dopaminergic (mDA) progenitors and subjected to ChIP-seq analysis to resolve genome-wide binding sites of forkhead box protein A2 (Foxa2). Foxa2 was found to directly regulate multiple lineage pathways to specify midbrain dopaminer...
ORGANISM(S): Mus musculus 
2012-07-01 | E-MTAB-1137 | biostudies-arrayexpress
TranscriptomicsRNA-seq of chemically reset human naive pluripotent stem cells
A simple method is presented to reset human pluripotent cells to a naive state via transient histone deacetylase inhibition and maintenance in chemically-defined naive stem cell culture media. Cells can be reset without transgenes and expanded continuously either on feeders or alternative substrates...
ORGANISM(S): Homo sapiens 
2017-08-07 | E-MTAB-5674 | biostudies-arrayexpress
TranscriptomicsRNA-seq of BMP response in glioblastoma-derived neural stem cells
The transcriptional response of normal and glioblastoma-derived neural (GNS) cells was profiled in self-renewing conditions and over a time course of differentiation in the presence of bone morphogenic protein (BMP).
ORGANISM(S): Homo sapiens 
2015-10-02 | E-MTAB-3867 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of PADI4 overexpression and inhibition in mouse embryonic stem cells
The enzymatic activity of PADI4 was investigated by overexpression and chemical inhibition to determine the effects of arginine citrullination on histone displacement, reprogramming efficiency and the maintenance of pluripotent stem cells.
ORGANISM(S): Mus musculus 
2013-11-22 | E-MTAB-1975 | biostudies-arrayexpress
TranscriptomicsMaskless photolithography genome tiling experiment
This experiment was designed to identify transcribed sequences across the human genome, particularly those distinct from previously annotated genes. To measure global transcriptional activity a series of high-density oligonucleotide tiling arrays was constructed to represent sense and antisense stra...
ORGANISM(S): Homo sapiens 
2004-10-29 | E-GEOD-1904 | biostudies-arrayexpress
TranscriptomicsRNA-seq read alignment evaluation
To assess the performance of read mapping software for RNA-seq, 26 spliced alignment protocols based on 11 programs and pipelines (BAGET, GEM, GSNAP, GSTRUCT, MapSplice, PALMapper, PASS, ReadsMap, SMALT, STAR and TopHat) were applied to four human and mouse transcriptome data sets.
ORGANISM(S): Homo sapiens 
2013-07-15 | E-MTAB-1728 | biostudies-arrayexpress
TranscriptomicsCross species comparison of expression patterns
Comparison of expression in liver samples of human, chimp, orang and rhesus, by using a novel multi-species cDNA array
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-2009 | biostudies-arrayexpress
UnknownDigital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival.
Not available
S-EPMC3556652 | biostudies-literature
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