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ProteomicsSuspension trapping (S-trap) is compatible with typical protein extraction buffers and detergents for bottom up proteomics
Analysis of cells and tissue by bottom up proteomics starts with lysis, followed by in-solution digestion. Lysis buffers commonly used include detergents and other reagents for efficient solubility of the proteins. However these reagents are, for the most part, incompatible with downstream analytica...
ORGANISM(S): Homo sapiens (Human) 
2019-02-28 | PXD011665 | Pride
Q eaxctive hf Lysis Proteomics Hela S-trap 
Unknown"She knows me best": a qualitative study of patient and caregiver views on the role of the primary care physician follow-up post-hospital discharge in individuals admitted with chronic obstructive pulmonary disease or congestive heart failure.
Not available
S-EPMC8421240 | biostudies-literature
TranscriptomicsSingle-cell RNA-sequencing data from developing embryonic human finger joints
A single cell atlas of developing human embryonic proximal and distal interphalangeal finger joints. This deposition holds the raw 10x single-cell sequencing data in FASTQ format and processed data in anndata format. All of the anndata objects contain normalised counts in the .X slot and gene names ...
ORGANISM(S): Homo sapiens 
2026-04-24 | E-MTAB-14722 | biostudies-arrayexpress
TranscriptomicsGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans
Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A growing literature suggests the hostM-bM-^@M-^Ys inflammatory response to the pathogen represents a potential tool to improve upon current diagno...
ORGANISM(S): Mus musculus 
2013-01-11 | E-GEOD-33341 | biostudies-arrayexpress
GenomicsORC precisely positions nucleosomes at origins of replication
The budding yeast genome is marked by 250-350 origins of DNA replication. These origins are bound by the origin recognition complex (ORC) throughout the cell cycle. ORC has known DNA binding sequence preferences which, though necessary for binding, are not sufficient to fully specify a genomic locus...
ORGANISM(S): Saccharomyces cerevisiae 
2010-03-19 | E-GEOD-16926 | biostudies-arrayexpress
TranscriptomicsThe fine-scale and complex architecture of human copy number variation
Despite considerable excitement over the potential functional significance of copy number variants (CNVs), we still lack knowledge of the fine-scale architecture of the large majority of CNV regions in the human genome. In this study, we used a high-resolution array-based comparative genomic hybridi...
ORGANISM(S): Homo sapiens 
2008-01-23 | E-GEOD-9831 | biostudies-arrayexpress
UnknownTriple comorbid trajectories of tobacco, alcohol, and marijuana use as predictors of antisocial personality disorder and generalized anxiety disorder among urban adults.
Not available
S-EPMC4096323 | biostudies-literature
UnknownOutcomes by tumor subtype and treatment pattern in women with small, node-negative breast cancer: a multi-institutional study.
Not available
S-EPMC4076026 | biostudies-literature
TranscriptomicsmRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum
Schizophrenia (SCZ) is a common, disabling mental illness with high heritability but complex, poorly understood genetic etiology. As the first phase of a genomic convergence analysis of SCZ, we generated 16.7 billion nucleotides of short read, shotgun sequences of cDNA from post-mortem cerebellar c...
ORGANISM(S): Homo sapiens 
2009-08-29 | E-GEOD-12297 | biostudies-arrayexpress
MetabolomicsLC-MS/MS metabolomics unravels the resistant phenotype of carbapenemase-producing Enterobacteriaceae

Introduction: The degree of antimicrobial resistance demonstrated by carbapenemase-producing Enterobacteriaceae (CPE) represents a growing public health challenge. Conventional methods for detecting CPE involve culture-based techniques with lengthy incubation steps. There is a ne...

2025-08-04 | MTBLS10129 | MetaboLights
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