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UnknowniTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Not available
S-EPMC6042963 | biostudies-literature
UnknownCorazonin signaling integrates energy homeostasis and lunar phase to regulate aspects of growth and sexual maturation in Platynereis.
Not available
S-EPMC6969523 | biostudies-literature
UnknownPlectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
Not available
S-EPMC11893104 | biostudies-literature
ProteomicsProteome Profiling Identifies Markers for Inflammation-Related Tumor-Fibroblast Interaction in Colorectal Cancer
Inflammation has been identified as an important factor in cancer development and progression, including colorectal cancer [CRC]. To determine the role of inflammation and the specific contribution of activated fibroblasts in cancer development and progression we analyzed six human CRC tissue specim...
ORGANISM(S): Homo sapiens (Human) 
2018-10-17 | PXD006776 | Pride
Tissue proteomics Shotgun proteomics Mass spectrometry Colorectal cancer Q exactive orbitrap 
UnknownPhosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Not available
S-EPMC5656746 | biostudies-literature
UnknownA Gold-PROTAC Degrades the Oncogenic Tyrosine Kinase MERTK: Insights into the Degradome from a Steady-State System.
Not available
S-EPMC12813982 | biostudies-literature
UnknownDetermination of a Tumor-Promoting Microenvironment in Recurrent Medulloblastoma: A Multi-Omics Study of Cerebrospinal Fluid.
Not available
S-EPMC7352284 | biostudies-literature
ProteomicsSeasonally relevant changes in UV-A alter neurohormone levels and behavior via cOpsin1
Many animals exhibit strong seasonal rhythms in their physiology and behavior, but the sensors conveying the environmental input are still unknown. In our study we provide detailed light measurements from the natural habitat of the marine bristle worm Platynereis dumerilii, showing that the ratios b...
ORGANISM(S): Platynereis Dumerilii 
PXD014682 | panorama
ProteomicsDetermination of a tumor-promoting microenvironment in recurrent medulloblastoma: a multi-omics study of cerebrospinal fluid
Molecular characterization of medulloblastoma (MB) cell origin and properties is the basis for a well-defined classification system. However, limited data is available regarding the MB tumor microenvironment. Here we present a mass spectrometry-based multi-omics study of cerebrospinal fluid (CSF) fr...
ORGANISM(S): Homo sapiens (Human) 
2020-06-01 | PXD018226 | Pride
12 Medulloblastoma Lipidomics Eicosanoids Mass spectrometry Hypoxia Polarized macrophages High performance liquid chromatography 13-dihome Cerebrospinal fluid Proteomics Multi-omics Metabolomics 
OtherComprehensive Assessment of Proteins Regulated by Dexamethasone Reveals Novel Effects in Primary Human Peripheral Blood Mononuclear Cells.
Data from ProteomeXchange, PXD ID: PXD001416. File: PBMC_1_con_cyt1-4.mgf. Published as part of J Proteome Res. 2014 Oct 27 . From the Abstract: {{i}} Monitoring proteins involved in regulatory effects may help to improve our understanding of inflammation. We have analyzed proteome alterations indu...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320004830 | GPMDB
Resource Reanalysis 
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