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ProteomicsIn Situ Proximity Labeling Identifies Lewy Pathology Molecular Interactions in the Human Brain
The intracellular misfolding and accumulation of alpha-synuclein into structures collectively called LP is a central phenomenon for the pathogenesis of synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Understanding the molecular architecture of LP is crucial ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD028830 | Pride
In situ Biotinylation by antigen recognition Neuropathology Lewy pathology Alpha-synuclein 
TranscriptomicsRegulation of Pattern Recognition Receptors by the Apolipoprotein A-I Mimetic Peptide 4F
The apolipoprotein A-I (apoA-I) mimetic peptide 4F displays prominent anti-inflammatory properties, including the ability to reduce vascular macrophage content. Macrophages are a heterogenous group of cells, represented by two principal phenotypes, the classically activated M1 macrophage and an alt...
ORGANISM(S): Homo sapiens 
2012-09-30 | E-GEOD-36933 | biostudies-arrayexpress
UnknownBiotinylation by antibody recognition-a method for proximity labeling.
Not available
S-EPMC5790613 | biostudies-literature
UnknownExpression and Site-Specific Biotinylation of Human Cytosolic 5'-Nucleotidase 1A in <i>Escherichia coli</i>.
Not available
S-EPMC12195718 | biostudies-literature
TranscriptomicsCUT&ID of 8 targets in HCT116
We developed CUT&ID, that simultaneously profiles genome-wide DNA and protein associations of any endogenous target in its native state, from one sample in a single streamlined workflow, and with no need of cloning or transgenesis. CUT&ID is enabled by a single fusion protein combining TurboID, prot...
ORGANISM(S): Homo sapiens 
2025-12-28 | E-MTAB-16382 | biostudies-arrayexpress
TranscriptomicsIllumina Sentrix 6 mouse BeadChip gene expression analysis in mouse spinal cord in the EAE model of Multiple Sclerosis
The study assessed the efficacy of R-flurbiprofen in experimental autoimmune encephalomyelitis (EAE) models of multiple sclerosis in mice. R-flurbiprofen, also known as tarenflurbil, is the R-enantiomer of the cyclooxyygenase inhibitor S-flurbiprofen. It is ineffective in terms of cyclooxygenase inh...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-60847 | biostudies-arrayexpress
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