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TranscriptomicsDrosophila brain gene expression with age: mRNA profiling
Gene expression profile in fly brains during development
ORGANISM(S): Drosophila melanogaster 
2011-12-23 | E-GEOD-25007 | biostudies-arrayexpress
TranscriptomicsSmall RNA profiling in Drosophila wild-type and nbr[f02257] mutants
nbr/CG9247 gene regulates 3'end heterogeneity of a subset of miRNAs. It is not clear how broad this effect is on small RNA population. To address this, we compared small RNA population in wild-type and tmr[f02257] mutants. This approach identified more miRNAs whose 3'end heterogeneity was affected ...
ORGANISM(S): Drosophila melanogaster 
2011-11-01 | E-GEOD-32684 | biostudies-arrayexpress
MetabolomicsComputational mass spectrometry accelerates C=C position-resolved untargeted lipidomics using oxygen attachment dissociation
Mass spectrometry-based untargeted lipidomics has revealed the lipidome atlas of living organisms at the molecular species level. Despite the double bond (C=C) position being a crucial factor for enzyme preference, cellular membrane milieu, and biological activity, the C=C defined structures have no...
2022-11-09 | MTBLS5861 | MetaboLights
Unknownm1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration.
Not available
S-EPMC10651481 | biostudies-literature
MetabolomicsNon-redundant cardiolipin synthase family proteins shape lipid composition and stress resilience in Bacteroides fragilis

Gut-resident bacteria must withstand membrane-disrupting stresses such as bile acids to persist in the intestinal environment. The Bacteroidota are a dominant phylum of the human gut microbiota. However, the genes responsible for synthesis of membrane lipids in this phylum remain relatively uncha...

2026-10-06 | MTBLS11891 | MetaboLights
UnknowneIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS.
Not available
S-EPMC6485101 | biostudies-literature
UnknownThe microRNA miR-34 modulates ageing and neurodegeneration in Drosophila.
Not available
S-EPMC3326599 | biostudies-literature
ProteomicsACSS2 Upregulation Enhances Neuronal Resilience to Aging and Neurodegeneration
Epigenetic mechanisms, including histone acetylation, play a key role in learning and memory, with recent evidence of a role in neuronal function in Alzheimer’s disease and Related Dementia (ADRD). Acetyl-CoA sythetase 2 (ACSS2) is central to epigenetics and gene regulation, particularly in neurons,...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD048769 | Pride
Acss2 Aging Neuron Neurodegeneration 
UnknownAn arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis.
Not available
S-EPMC1440312 | biostudies-literature
UnknownSpt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts.
Not available
S-EPMC5823025 | biostudies-literature
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