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MetabolomicsUse of UHPLC-HRMS to profile the metabolites from the serum of breast cancer patients

Breast cancer (BC) is the most common malignancy and the leading cause of cancer-related mortality in women worldwide. As such exploring the metabolic changes during human breast carcinogenesis is important for developing disease prevention methods and treatments. In the present study, non-target...

2024-02-13 | MTBLS8920 | MetaboLights
ProteomicsBreast cancer tumors
The project analyzed 88 breast cancer clinical samples, including lymph node negative and positive primary tumors, lymph node metastases, and healthy tissue as control. All samples were combined with a super-SILAC mix that served as an internal standard for quantification.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-06-16 | MSV000079830 | MassIVE
TranscriptomicsGene expression profiling of invasive breast cancer events from the tamoxifen prevention trial
Gene expression profiling of invasive breast cancer events from the tamoxifen prevention trial validates low estrogen receptor mRNA level as the main determinant of tamoxifen resistance in estrogen receptor positive breast cancer. In NSABP Breast Cancer Prevention Trial (BCPT), tamoxifen reduced th...
ORGANISM(S): Homo sapiens 
2011-12-08 | E-GEOD-12665 | biostudies-arrayexpress
ProteomicsProteomic characterization of MDA-MB-231 and MCF-10A breast cells exposed to 1 mT 50 Hz ELF for 4 hours
MDA-MB-231 breast cancer cells and MCF-10A breast cells were exposed to 1 mT 50 Hz extremely low-frequency magnetic field (ELF-MF) for 4 hours
ORGANISM(S): Homo Sapiens (human) 
2023-02-17 | PXD040120 | JPOST Repository
ProteomicsProteogenomics Connects Somatic Mutations to Signalling in Breast Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-08-28 | MSV000084248 | MassIVE
TranscriptomicsIdentification of a novel ESR1 transcript variant in breast cancer cells by RNA capture-sequencing
RNA capture-sequencing analysis was carried out to study the usage of ESR1 exons and transcripts in different breast cancer models, including both ERα(+) and ERα(-) cell lines. Total RNA was extracted and processed for the analysis.
ORGANISM(S): Homo sapiens 
2022-08-29 | E-MTAB-10733 | biostudies-arrayexpress
GenomicsBreast cancer prevention with liquiritigenin
Breast cancer prevention with liquiritigenin
PRJNA926640 | ENA
TranscriptomicsPML regulates PPAR signaling and fatty acid oxidation in breast cancer
Cancer cells exhibit an aberrant metabolism which facilitates more efficient production of biomass, and hence tumor growth and progression. The genetic cues modulating this metabolic switch remain largely undetermined, however. Here we identify a metabolic function for PML which reveals an unexpecte...
ORGANISM(S): Mus musculus 
2013-01-29 | E-GEOD-39220 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human breast cancer brain metastases in a mouse xenograft model with vehicle of vorinostat treatment
Gene Expression Profiling of a Mouse Xenograft Model of â??Triple-Negativeâ?? Breast Cancer Brain Metastases With and Without Vorinostat Treatment. Purpose: As chemotherapy and molecular therapy improve the systemic survival of breast cancer patients, the incidence of brain metastases increases. Few...
ORGANISM(S): Homo sapiens 
2009-10-27 | E-GEOD-18544 | biostudies-arrayexpress
UnknownMammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years.
Not available
S-EPMC7523310 | biostudies-literature
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