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TranscriptomicsTranscription profiling by array of mouse embryonic stem cell lines with Dgcr8 mutations to investigate the broad role of miRNAs and individual miRNAs through the reintroduction of miRNA mimics
These experiments were conducted as part of a study to derive the targets of miRNAs. Two independent BayGenomics mouse embryonic stem cell lines (XH157 and XG058), each bearing a gene trap between exons 9 and 10 of the Dgcr8 locus (ENSMUST00000115633, Ensembl v53) were further mutagenised by the tar...
ORGANISM(S): Mus musculus 
2012-08-20 | E-MTAB-418 | biostudies-arrayexpress
TranscriptomicsGenotyping of human glioma - assessing the significance of chromosomal aberrations in cancer
Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics and targeted therapeutics. Systematic efforts to analyze cancer genomes are underway, but the analysis is hampered by the lack of a statistical framework to distinguish mean...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-9635 | biostudies-arrayexpress
ProteomicsTime-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome
The acetyltransferases CBP and p300 are multifunctional transcriptional co-activators; however, their acetylation targets, site-specific acetylation kinetics, and function in proteome regulation are incompletely understood. We combined quantitative proteomics with novel CBP/p300-specific catalytic i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
MSV000095981 | MassIVE
UnknownStructure-Based Discovery and Structural Basis of a Novel Broad-Spectrum Natural Product against the Main Protease of Coronavirus.
Not available
S-EPMC8754229 | biostudies-literature
TranscriptomicsTranscriptional profiles from Dickeya dadantii 3937 in various growth conditions
We have analysed the global gene expression of the plant pathogen Dickeya dadantii 3937 when grown in vitro under different growth and stress conditions. A multi-factorial design with 32 different experimental conditions was constructed, with two biological replicates for each condition. Cells were ...
ORGANISM(S): Dickeya dadantii 3937 
2015-04-16 | E-MTAB-541 | biostudies-arrayexpress
UnknownLipidomics of Huntington's Disease: A Comprehensive Review of Current Status and Future Directions.
Not available
S-EPMC11766911 | biostudies-literature
UnknownExperimental West Nile Virus Infection in Rabbits: An Alternative Model for Studying Induction of Disease and Virus Control.
Not available
S-EPMC4584271 | biostudies-literature
TranscriptomicsMating-induced transcriptional changes in the head of female of Anopheles gambiae mosquitoes at three time points (3, 12 and 24 hours) post mating
To gain insight into the molecular pathways and processes controlling the behavioral and physiological shift induced by copulation in An. gambiae, we performed an in-depth transcriptional analysis of the heads of mated females. We analyzed three time points post-mating (3, 12 and 24 hours post matin...
ORGANISM(S): Anopheles gambiae 
2020-09-23 | E-MTAB-8733 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse TGF-a induction in saccular phase and alveolar phase lung morphogenesis in mice
Effect of TGFa induction on saccular phase or alveolar phase lung morphogenesis in mice.
ORGANISM(S): Mus musculus 
2022-11-21 | E-MEXP-698 | biostudies-arrayexpress
GenomicsGlobal Mapping of Histone H3 K4 and K27 Trimethylation: Lineage Fate Determination of Differentiating CD4+ T Cells
Multipotential naïve CD4+ T cells differentiate into distinct lineages including Th1, Th2, Th17, and inducible T regulatory (iTreg) cells. The remarkable diversity of CD4+ T cells begs the question whether the observed changes reflect terminal differentiation with heritable epigenetic modifications ...
ORGANISM(S): Mus musculus 
2009-01-21 | E-GEOD-14254 | biostudies-arrayexpress
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